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    ash2 Set1C complex and Lid2 complex subunit Ash2-trithorax family [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539667, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ash2
    Official Full Name
    Set1C complex and Lid2 complex subunit Ash2-trithorax family
    Primary source
    PomBase:SPBC13G1.08c
    Locus tag
    SPOM_SPBC13G1.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ash2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3738915..3741393, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene folding protein Neighboring gene ncRNA Neighboring gene alpha-ketoglutarate-dependent dioxygenase Neighboring gene ncRNA Neighboring gene Fe-sulfur cluster assembly protein Isd11 Neighboring gene palmitoyltransferase Swf1 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene bystin family U3 and U14 snoRNA associated protein Neighboring gene ATP-dependent RNA helicase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Ash2, a subunit of histone H3K4 methyltransferase complex, is involved in the sporulation in Schizosaccharomyces pombe]. Wang W, et al. Yi Chuan, 2014 Sep. PMID 25252312
    2. Histone H2B ubiquitylation promotes activity of the intact Set1 histone methyltransferase complex in fission yeast. Racine A, et al. J Biol Chem, 2012 Jun 1. PMID 22505722, Free PMC Article
    3. High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts. Roguev A, et al. J Biol Chem, 2003 Mar 7. PMID 12488447
    4. A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Roguev A, et al. Mol Cell Proteomics, 2004 Feb. PMID 14617822
    5. The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components. Salas-Pino S, et al. J Cell Biol, 2017 Nov 6. PMID 28974540, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Ash2, a subunit of histone H3K4 methyltransferase complex, is involved in the sporulation.
      Title: [Ash2, a subunit of histone H3K4 methyltransferase complex, is involved in the sporulation in Schizosaccharomyces pombe].
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of gene expression, epigenetic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Lid2 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Set1C/COMPASS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Set1C/COMPASS complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromatin IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Set1C complex and Lid2 complex subunit Ash2-trithorax family

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3738915..3741393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022478.3 → NP_596557.1  Set1C complex and Lid2 complex subunit Ash2-trithorax family [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596557.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60070
      Conserved Domains (2) summary
      cd15583
      Location:42 → 91
      PHD_ash2p_like; PHD finger found in Schizosaccharomyces pombe Set1 complex component ash2 (spAsh2p) and similar proteins
      cd12872
      Location:361 → 584
      SPRY_Ash2; SPRY domain in Ash2
    Nucleotide Protein
    Heading Accession and Version

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