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    trm10 tRNA m(1)G methyltransferase Trm10 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543319, updated on 18-Sep-2024

    Summary

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    Official Symbol
    trm10
    Official Full Name
    tRNA m(1)G methyltransferase Trm10
    Primary source
    PomBase:SPAC6B12.09
    Locus tag
    SPOM_SPAC6B12.09
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See trm10 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (2427935..2429090)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATPase co-chaperone protein Neighboring gene ncRNA Neighboring gene ribosome assembly protein Rsa3 Neighboring gene DNA primase catalytic subunit Spp1 Neighboring gene ncRNA Neighboring gene DNA replication preinitiation complex assembly protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate. Shao Z, et al. Nucleic Acids Res, 2014 Jan. PMID 24081582, Free PMC Article
    2. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article
    3. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The findings revealed that Trm10 is a new member of the SpoU-TrmD (SPOUT) MTase superfamily.
      Title: Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables tRNA (guanosine(9)-N1)-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA N1-guanine methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA N1-guanine methylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tRNA m(1)G methyltransferase Trm10

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2427935..2429090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019194.3 → NP_593764.1  tRNA m(1)G methyltransferase Trm10 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593764.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14214
      Conserved Domains (1) summary
      pfam01746
      Location:105 → 273
      tRNA_m1G_MT; tRNA (Guanine-1)-methyltransferase
    Nucleotide Protein
    Heading Accession and Version

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