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    rox3 mediator complex subunit Med19 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539249, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rox3
    Official Full Name
    mediator complex subunit Med19
    Primary source
    PomBase:SPCC1450.05c
    Locus tag
    SPOM_SPCC1450.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    med19
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    Genomic context

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    See rox3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1734260..1735312, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ribonucleoprotein complex protein Utp502 Neighboring gene ncRNA Neighboring gene translation elongation factor EF-1 beta subunit, guanyl-nucleotide exchange factor (eEF1B) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CIA machinery monothiol glutaredoxin Grx3 Neighboring gene D-amino acid oxidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells. Spåhr H, et al. Proc Natl Acad Sci U S A, 2001 Oct 9. PMID 11572939, Free PMC Article
    2. Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system. Tamayo E, et al. Eur J Biochem, 2004 Jun. PMID 15182371
    3. Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nozawa K, et al. Nature, 2017 May 11. PMID 28467824
    4. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article
    5. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med19

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1734260..1735312 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023294.3 → NP_588304.1  mediator complex subunit Med19 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588304.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y7N2
      Conserved Domains (1) summary
      pfam08633
      Location:18 → 62
      Rox3; Rox3 mediator complex subunit
    Nucleotide Protein
    Heading Accession and Version

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