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    hrd3 HRD ubiquitin ligase complex subunit [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540568, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hrd3
    Official Full Name
    HRD ubiquitin ligase complex subunit
    Primary source
    PomBase:SPBC28F2.08c
    Locus tag
    SPOM_SPBC28F2.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See hrd3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1581815..1584288, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene xylose and arabinose reductase Neighboring gene ncRNA Neighboring gene Prp19 complex subunit Cwf7 Neighboring gene ERMES complex subunit, membrane tether and lipid transfer protein Mdm12 Neighboring gene DNA recombination mediator Sfr1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transcription factor TFIIA complex large subunit Toa1 Neighboring gene SAGA complex subunit Ngg1/Ada3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038
    2. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
    3. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ERAD pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of Hrd1p ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in endoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    HRD ubiquitin ligase complex subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1581815..1584288 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021564.3 → NP_595669.1  HRD ubiquitin ligase complex subunit [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595669.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78930, P78931, Q9USV0
      Conserved Domains (4) summary
      smart00671
      Location:527 → 557
      SEL1; Sel1-like repeats
      COG0790
      Location:472 → 561
      TPR; TPR repeat [Signal transduction mechanisms]
      sd00010
      Location:473 → 502
      SLR; SLR repeat [structural motif]
      pfam08238
      Location:280 → 315
      Sel1; Sel1 repeat
    Nucleotide Protein
    Heading Accession and Version

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