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    hal4 serine/threonine protein kinase Hal4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542804, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hal4
    Official Full Name
    serine/threonine protein kinase Hal4
    Primary source
    PomBase:SPAC29A4.16
    Locus tag
    SPOM_SPAC29A4.16
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ppk10; sat4
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    Genomic context

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    See hal4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5113913..5116634, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene Ca(2+)/Mn(2+)-transporting P-type ATPase P5 type Cta5 Neighboring gene ncRNA Neighboring gene histone chaperone, Clr6 and Rpd3L complex subunit Prw1 Neighboring gene ncRNA Neighboring gene integral mitochondrial outer membrane (MOM) protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine--tRNA (Ser) ligase Srs1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel pathway determining multidrug sensitivity in Schizosaccharomyces pombe. Thornton G, et al. Genes Cells, 2005 Oct. PMID 16164595
    2. Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase. Wang LY, et al. Mol Cell Biol, 2005 May. PMID 15870269, Free PMC Article
    3. Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. Tanae K, et al. PLoS One, 2012. PMID 22291963, Free PMC Article
    4. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular monoatomic cation homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular potassium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    serine/threonine protein kinase Hal4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5113913..5116634 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020295.3 → NP_594866.1  serine/threonine protein kinase Hal4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594866.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14019
      Conserved Domains (3) summary
      smart00220
      Location:355 → 623
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      COG3266
      Location:52 → 211
      DamX; Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning]
      cd13994
      Location:357 → 623
      STKc_HAL4_like; Catalytic domain of Fungal Halotolerance protein 4-like Serine/Threonine kinases
    Nucleotide Protein
    Heading Accession and Version

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