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    git3 G-protein-coupled receptor Git3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538770, updated on 18-Sep-2024

    Summary

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    Official Symbol
    git3
    Official Full Name
    G-protein-coupled receptor Git3
    Primary source
    PomBase:SPCC1753.02c
    Locus tag
    SPOM_SPCC1753.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See git3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1542333..1546095, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene eRF3-like class 2 translation release factor sup35 Neighboring gene SNARE-binding protein Sec1 Neighboring gene single-stranded DNA-binding protein Ssb2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene meiotic recombination protein Rec7 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glucose monitoring in fission yeast via the Gpa2 galpha, the git5 Gbeta and the git3 putative glucose receptor. Welton RM, et al. Genetics, 2000 Oct. PMID 11014802, Free PMC Article
    2. The phospholipase B homolog Plb1 is a mediator of osmotic stress response and of nutrient-dependent repression of sexual differentiation in the fission yeast Schizosaccharomyces pombe. Yang P, et al. Mol Genet Genomics, 2003 Apr. PMID 12715160, Free PMC Article
    3. Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast. Roux AE, et al. PLoS Genet, 2009 Mar. PMID 19266076, Free PMC Article
    4. Sck1 negatively regulates Gpa2-mediated glucose signaling in Schizosaccharomyces pombe. Mudge DK, et al. Eukaryot Cell, 2014 Feb. PMID 24297439, Free PMC Article
    5. Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein alpha subunit encoded by gpa2 (git8). Nocero M, et al. Genetics, 1994 Sep. PMID 8001792, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GIT3 is responsible for the pro-aging effects of glucose in fission yeast.
      Title: Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables G protein-coupled glucose receptor activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of induction of conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    G-protein-coupled receptor Git3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1542333..1546095 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023218.3 → NP_588228.1  G-protein-coupled receptor Git3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588228.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94744
      Conserved Domains (1) summary
      pfam11710
      Location:27 → 219
      Git3; G protein-coupled glucose receptor regulating Gpa2
    Nucleotide Protein
    Heading Accession and Version

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