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    rpa12 DNA-directed RNA polymerase complex I TFIIS subunit Rpa12 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538906, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rpa12
    Official Full Name
    DNA-directed RNA polymerase complex I TFIIS subunit Rpa12
    Primary source
    PomBase:SPCC1259.03
    Locus tag
    SPOM_SPCC1259.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rpa12 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (1040100..1041016)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene metallopeptidase 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ino80 complex subunit Iec3 Neighboring gene cytochrome c oxidase subunit VIIa

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional architecture of the Reb1-Ter complex of Schizosaccharomyces pombe. Jaiswal R, et al. Proc Natl Acad Sci U S A, 2016 Apr 19. PMID 27035982, Free PMC Article
    2. Isolation and characterization of the fission yeast gene Sprpa12+ reveals that the conserved C-terminal zinc-finger region is dispensable for the function of its product. Imazawa Y, et al. Mol Gen Genet, 2001 Feb. PMID 11254133
    3. Conserved strategies of RNA polymerase I hibernation and activation. Heiss FB, et al. Nat Commun, 2021 Feb 3. PMID 33536435, Free PMC Article
    4. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Nguyen TT, et al. Sci Rep, 2015 Feb 11. PMID 25669599, Free PMC Article
    5. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to RNA polymerase I activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in termination of RNA polymerase I transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in termination of RNA polymerase I transcription IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase I EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase I complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase I complex IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase complex I TFIIS subunit Rpa12

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1040100..1041016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023051.3 → NP_588059.1  DNA-directed RNA polymerase complex I TFIIS subunit Rpa12 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588059.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94703
      Conserved Domains (1) summary
      COG1594
      Location:6 → 118
      RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]
    Nucleotide Protein
    Heading Accession and Version

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