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    elg1 DNA replication factor C complex subunit Elg1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541276, updated on 18-Sep-2024

    Summary

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    Official Symbol
    elg1
    Official Full Name
    DNA replication factor C complex subunit Elg1
    Primary source
    PomBase:SPBC947.11c
    Locus tag
    SPOM_SPBC947.11C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See elg1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (649883..652980)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase II-associated protein Neighboring gene protein Kms2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase E3 Neighboring gene ncRNA Neighboring gene ThiJ domain protein, glyoxylase III

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast. Tamang S, et al. Elife, 2019 May 31. PMID 31149897, Free PMC Article
    2. Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast. Kim J, et al. Nucleic Acids Res, 2005. PMID 16040599, Free PMC Article
    3. In vitro reconstitution of the Schizosaccharomyces pombe alternative excision repair pathway. Alleva JL, et al. Biochemistry, 2000 Mar 14. PMID 10704216
    4. Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast. Koch A, et al. Sci Signal, 2011 Jun 28. PMID 21712547
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PCNA unloading by Elg1 is necessary to limit Fbh1 and Srs2 activity, and thereby enable recombination to proceed.
      Title: The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity ISM
    Inferred from Sequence Model
    more info
    		  
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA clamp loader activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables DNA clamp unloader activity IC
    Inferred by Curator
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA recombination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in UV-damage excision repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic DNA replication ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in telomere maintenance ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of Elg1 RFC-like complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromatin IC
    Inferred by Curator
    more info
    		  
    is_active_in chromosome, telomeric repeat region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol HDA PubMed 
    part_of nuclear DNA replication factor C complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DNA replication factor C complex subunit Elg1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      649883..652980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021172.3 → NP_595265.1  DNA replication factor C complex subunit Elg1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595265.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O43086
      Conserved Domains (1) summary
      cl21455
      Location:428 → 538
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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