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    mcp60 protein Mcp60 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543131, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mcp60
    Official Full Name
    protein Mcp60
    Primary source
    PomBase:SPAC12G12.04
    Locus tag
    SPOM_SPAC12G12.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    hsp60
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    Genomic context

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    See mcp60 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (339766..342097, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene rRNA processing protein Neighboring gene SAGA complex/transcription factor TFIID complex subunit Taf9 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA-binding protein Cip2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. H₂O₂ stress-specific regulation of S. pombe MAPK Sty1 by mitochondrial protein phosphatase Ptc4. Di Y, et al. EMBO J, 2012 Feb 1. PMID 22139357, Free PMC Article
    2. Targeting mitochondrial transcription in fission yeast with ETB, an inhibitor of HSP60, the chaperone that binds to the mitochondrial transcription factor Mtf1. Sun W, et al. Genes Cells, 2012 Feb. PMID 23035257
    3. Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences. Backes S, et al. J Cell Biol, 2018 Apr 2. PMID 29382700, Free PMC Article
    4. Identification of novel coenzyme Q(10) biosynthetic proteins Coq11 and Coq12 in Schizosaccharomyces pombe. Nishida I, et al. J Biol Chem, 2023 Jun. PMID 37156397, Free PMC Article
    5. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ATP hydrolysis activity IC
    Inferred by Curator
    more info
    		  
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-folding chaperone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial unfolded protein response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein refolding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrial intermembrane space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitochondrial nucleoid ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in mitochondrion HDA PubMed 
    part_of post-mRNA release spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein Mcp60

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      339766..342097 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018294.3 → NP_592894.1  protein Mcp60 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592894.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09864, Q10285
      Conserved Domains (2) summary
      PTZ00114
      Location:29 → 564
      PTZ00114; Heat shock protein 60; Provisional
      cd03344
      Location:35 → 558
      GroEL; GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found ...
    Nucleotide Protein
    Heading Accession and Version

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