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    ulp2 SUMO deconjugating cysteine peptidase Ulp2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542268, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ulp2
    Official Full Name
    SUMO deconjugating cysteine peptidase Ulp2
    Primary source
    PomBase:SPAC17A5.07c
    Locus tag
    SPOM_SPAC17A5.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ulp2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003424.3 (1764233..1766733, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene transcription factor TFIIH complex ERCC-3 subunit Ptr8 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene COPII-coated vesicle-associated protein Erp2/3/4 Neighboring gene protein phosphatase regulatory subunit Glc8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pli1(PIAS1) SUMO ligase protected by the nuclear pore-associated SUMO protease Ulp1SENP1/2. Nie M, et al. J Biol Chem, 2015 Sep 11. PMID 26221037, Free PMC Article
    2. DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes. Prudden J, et al. Mol Cell Biol, 2011 Jun. PMID 21444718, Free PMC Article
    3. Functional Crosstalk between the PP2A and SUMO Pathways Revealed by Analysis of STUbL Suppressor, razor 1-1. Nie M, et al. PLoS Genet, 2016 Jul. PMID 27398807, Free PMC Article
    4. A genetic screen for functional partners of condensin in fission yeast. Robellet X, et al. G3 (Bethesda), 2014 Feb 19. PMID 24362309, Free PMC Article
    5. The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2. Jongjitwimol J, et al. PLoS One, 2014. PMID 24818994, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables SUMO-specific endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables deSUMOylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein desumoylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cytoplasmic translation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SUMO deconjugating cysteine peptidase Ulp2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1764233..1766733 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018908.3 → NP_593475.2  SUMO deconjugating cysteine peptidase Ulp2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593475.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13769
      Conserved Domains (3) summary
      COG5160
      Location:25 → 592
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      pfam02902
      Location:361 → 595
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain
      pfam05937
      Location:230 → 312
      EB1_binding; EB-1 Binding Domain
    Nucleotide Protein
    Heading Accession and Version

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