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    leucine--tRNA (Leu) ligase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543476, updated on 18-Sep-2024

    Summary

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    Official Full Name
    leucine--tRNA (Leu) ligase
    Primary source
    PomBase:SPAC4G8.09
    Locus tag
    SPOM_SPAC4G8.09
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (778400..781324)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial iron ion transporter Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F1-F0 ATPase assembly protein Neighboring gene SNARE protein Gos1 Neighboring gene ncRNA Neighboring gene alpha-1,2-mannosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    2. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    3. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
    4. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe: highly homologous introns are inserted at the same position of the otherwise less conserved cox1 genes in Schizosaccharomyces pombe and Aspergillus nidulans. Lang BF. EMBO J, 1984 Sep. PMID 6092057, Free PMC Article
    5. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe. The cytochrome b gene has an intron closely related to the first two introns in the Saccharomyces cerevisiae cox1 gene. Lang BF, et al. J Mol Biol, 1985 Aug 5. PMID 4046021

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables leucine-tRNA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in Group I intron splicing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in leucyl-tRNA aminoacylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IC
    Inferred by Curator
    more info
    		  
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leucine--tRNA (Leu) ligase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      778400..781324
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018467.3 → NP_593069.1  leucine--tRNA (Leu) ligase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593069.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09828
      Conserved Domains (4) summary
      cd00812
      Location:59 → 667
      LeuRS_core; catalytic core domain of leucyl-tRNA synthetases
      PRK00390
      Location:33 → 872
      leuS; leucyl-tRNA synthetase; Validated
      pfam13603
      Location:247 → 414
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
      cl12020
      Location:667 → 791
      Anticodon_Ia_like; Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials