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    gbs1 glucosidase II beta subunit Gbs1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538725, updated on 18-Sep-2024

    Summary

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    Official Symbol
    gbs1
    Official Full Name
    glucosidase II beta subunit Gbs1
    Primary source
    PomBase:SPCC825.02
    Locus tag
    SPOM_SPCC825.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    gls2beta
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    Genomic context

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    See gbs1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003421.2 (1025524..1027919)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase Ucp12 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATP-binding cassette protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene plasma membrane SNARE Psy1 Neighboring gene putative histone N-acetyltransferase Naa40 Neighboring gene splicing coactivator Pwi1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of the lectin mannose 6-phosphate receptor homology (MRH) domain of glucosidase II, an enzyme that regulates glycoprotein folding quality control in the endoplasmic reticulum. Olson LJ, et al. J Biol Chem, 2013 Jun 7. PMID 23609449, Free PMC Article
    2. Glucosidase II beta subunit modulates N-glycan trimming in fission yeasts and mammals. Stigliano ID, et al. Mol Biol Cell, 2009 Sep. PMID 19605557, Free PMC Article
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables D-mannose binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables enzyme regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables enzyme-substrate adaptor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables mannan binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in N-glycan processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in N-glycan processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum lumen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of glucosidase II complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    glucosidase II beta subunit Gbs1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1025524..1027919
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023044.3 → NP_588052.1  glucosidase II beta subunit Gbs1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588052.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78894, Q9USH8
      Conserved Domains (2) summary
      pfam12999
      Location:9 → 180
      PRKCSH-like; Glucosidase II beta subunit-like
      pfam13015
      Location:346 → 506
      PRKCSH_1; Glucosidase II beta subunit-like protein
    Nucleotide Protein
    Heading Accession and Version

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