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    ssc1 chaperone Ssc1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543026, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ssc1
    Official Full Name
    chaperone Ssc1
    Primary source
    PomBase:SPAC664.11
    Locus tag
    SPOM_SPAC664.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ssp1
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    Genomic context

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    See ssc1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1725752..1728189)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene kinesin-14 family minus-end directed microtubule motor Klp2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene succinate dehydrogenase assembly factor 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dual modes of transcriptional and translational initiation of SSP1, the gene for a mitochondrial HSP70, responding to heat-shock in Schizosaccharomyces pombe. Kasai H, et al. Nucleic Acids Res, 1991 Oct 11. PMID 1923816, Free PMC Article
    2. Isolation of a gene encoding a mitochondrial HSP70 protein from Schizosaccharomyces pombe. Powell MJ, et al. Gene, 1990 Oct 30. PMID 2123810
    3. Iron-Sulfur Cluster Biogenesis Chaperones: Evidence for Emergence of Mutational Robustness of a Highly Specific Protein-Protein Interaction. Delewski W, et al. Mol Biol Evol, 2016 Mar. PMID 26545917, Free PMC Article
    4. Ribosome recycling defects modify the balance between the synthesis and assembly of specific subunits of the oxidative phosphorylation complexes in yeast mitochondria. Ostojić J, et al. Nucleic Acids Res, 2016 Jul 8. PMID 27257059, Free PMC Article
    5. A chaperone-assisted degradation pathway targets kinetochore proteins to ensure genome stability. Kriegenburg F, et al. PLoS Genet, 2014 Jan. PMID 24497846, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Hsp104 and Hsp70-type chaperones are required for efficient degradation of Sdj1-L169P.
      Title: A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heat shock protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein folding chaperone IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in [2Fe-2S] cluster assembly EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in chaperone cofactor-dependent protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in iron-sulfur cluster assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    involved_in protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of PAM complex, Tim23 associated import motor ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chaperone Ssc1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1725752..1728189
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018892.3 → NP_593459.1  chaperone Ssc1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593459.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P22774
      Conserved Domains (2) summary
      cd11733
      Location:49 → 425
      HSPA9-like_NBD; Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins
      PRK00290
      Location:49 → 671
      dnaK; molecular chaperone DnaK; Provisional
    Nucleotide Protein
    Heading Accession and Version

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