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    itr2 plasma membrane myo-inositol transmembrane transporter [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541827, updated on 18-Sep-2024

    Summary

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    Official Symbol
    itr2
    Official Full Name
    plasma membrane myo-inositol transmembrane transporter
    Primary source
    PomBase:SPAC20G8.03
    Locus tag
    SPOM_SPAC20G8.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See itr2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1393605..1395820)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene DDHD family phospholipase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene electron transfer flavoprotein-ubiquinone oxidoreductase Neighboring gene ncRNA Neighboring gene F-BAR domain protein Cdc15

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Exogenous inositol and genes responsible for inositol transport are required for mating and sporulation in Shizosaccharomyces pombe. Niederberger C, et al. Curr Genet, 1998 Apr. PMID 9560432
    2. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article
    3. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables myo-inositol:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables myo-inositol:proton symporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables myo-inositol:proton symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in myo-inositol import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in myo-inositol import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    plasma membrane myo-inositol transmembrane transporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1393605..1395820
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018751.3 → NP_593320.1  plasma membrane myo-inositol transmembrane transporter [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593320.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78901, P87110
      Conserved Domains (2) summary
      cd06174
      Location:86 → 519
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam00083
      Location:84 → 534
      Sugar_tr; Sugar (and other) transporter
    Nucleotide Protein
    Heading Accession and Version

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