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    cwf24 zf-C3HC4 domain-containing and GCN5-like protein cwf24 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540186, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cwf24
    Official Full Name
    zf-C3HC4 domain-containing and GCN5-like protein cwf24
    Primary source
    PomBase:SPBC13E7.02
    Locus tag
    SPOM_SPBC13E7.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See cwf24 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3041461..3043524)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene 4-phosphoerythronate phosphatase/2-phosphoglycolate phophatase, involved in detoxification of glycolytic by-products Neighboring gene ncRNA Neighboring gene splicing factor Cwf22 Neighboring gene RNA hairpin-binding protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Carnahan RH, et al. Eukaryot Cell, 2005 Mar. PMID 15755920, Free PMC Article
    2. The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast. Kallgren SP, et al. PLoS Genet, 2014. PMID 24874881, Free PMC Article
    3. Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Ohi MD, et al. Mol Cell Biol, 2002 Apr. PMID 11884590, Free PMC Article
    4. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article
    5. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables N-acetyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		  
    enables ubiquitin protein ligase activity ISM
    Inferred from Sequence Model
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in snoRNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U2-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zf-C3HC4 domain-containing and GCN5-like protein cwf24

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3041461..3043524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022177.3 → NP_596257.1  zf-C3HC4 domain-containing and GCN5-like protein cwf24 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596257.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P6R8
      Conserved Domains (5) summary
      COG0456
      Location:404 → 523
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      COG5152
      Location:24 → 314
      COG5152; Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers [General function prediction only]
      pfam00583
      Location:425 → 499
      Acetyltransf_1; Acetyltransferase (GNAT) family
      pfam00642
      Location:185 → 211
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam13923
      Location:254 → 291
      zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
    Nucleotide Protein
    Heading Accession and Version

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