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    srp1 pre-mRNA-splicing factor srp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539818, updated on 18-Sep-2024

    Summary

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    Official Symbol
    srp1
    Official Full Name
    pre-mRNA-splicing factor srp1
    Primary source
    PomBase:SPBC11C11.08
    Locus tag
    SPOM_SPBC11C11.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See srp1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (3362844..3364515)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene tRNA-Pro Neighboring gene ncRNA Neighboring gene 60S ribosomal protein L18 Neighboring gene ncRNA Neighboring gene 60S ribosomal protein L5 Neighboring gene tRNA pseudouridine synthase Neighboring gene ATP-dependent DNA helicase Irc3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Srp2, an SR protein family member of fission yeast: in vivo characterization of its modular domains. Lützelberger M, et al. Nucleic Acids Res, 1999 Jul 1. PMID 10373577, Free PMC Article
    2. Identification and characterization of srp1, a gene of fission yeast encoding a RNA binding domain and a RS domain typical of SR splicing factors. Gross T, et al. Nucleic Acids Res, 1998 Jan 15. PMID 9421507, Free PMC Article
    3. Interactions between two fission yeast serine/arginine-rich proteins and their modulation by phosphorylation. Tang Z, et al. Biochem J, 2002 Dec 1. PMID 12186627, Free PMC Article
    4. Biochemical and genetic conservation of fission yeast Dsk1 and human SR protein-specific kinase 1. Tang Z, et al. Mol Cell Biol, 2000 Feb. PMID 10629038, Free PMC Article
    5. Dsk1p kinase phosphorylates SR proteins and regulates their cellular localization in fission yeast. Tang Z, et al. Biochem J, 2007 Jul 1. PMID 17362205, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Translin binds the pre-mRNA-splicing factor srp1 and vip1, a protein conserved in fungi.
      Title: Identification of proteins that form specific complexes with the highly conserved protein Translin in Schizosaccharomyces pombe.
    2. Data show that Srp1p and Srp2p are the in vivo substrates of Dsk1p in Schizosaccharomyces pombe
      Title: Dsk1p kinase phosphorylates SR proteins and regulates their cellular localization in fission yeast.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-mRNA-splicing factor srp1
    NP_596398.1
    • SR family protein, human SRFS2 ortholog Srp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3362844..3364515
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022318.3 → NP_596398.1  pre-mRNA-splicing factor srp1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596398.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74305, Q10193
      Conserved Domains (1) summary
      cd12467
      Location:8 → 85
      RRM_Srp1p_like; RNA recognition motif 1 in fission yeast pre-mRNA-splicing factor Srp1p and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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