U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    yth1 cleavage and polyadenylation specificity factor complex subunit Yth1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541506, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    yth1
    Official Full Name
    cleavage and polyadenylation specificity factor complex subunit Yth1
    Primary source
    PomBase:SPAC227.08c
    Locus tag
    SPOM_SPAC227.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See yth1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (510410..511364, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene serine/threonine protein phosphatase PP2A regulatory subunit B-55 Pab1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene folylpolyglutamate synthase Neighboring gene prefoldin subunit 2 Neighboring gene putative misfolded glycoprotein sensor Yos9

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. An enhancer screen identifies new suppressors of small-RNA-mediated epigenetic gene silencing. Shimada Y, et al. PLoS Genet, 2021 Jun. PMID 34157021, Free PMC Article
    2. The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Wittmann S, et al. Nat Commun, 2017 Apr 3. PMID 28367989, Free PMC Article
    3. CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing. Vo TV, et al. Cell Rep, 2019 Jul 2. PMID 31269446, Free PMC Article
    4. A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Roguev A, et al. Mol Cell Proteomics, 2004 Feb. PMID 14617822
    5. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. An enhancer screen identifies new suppressors of small-RNA-mediated epigenetic gene silencing.
      Title: An enhancer screen identifies new suppressors of small-RNA-mediated epigenetic gene silencing.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    part_of mRNA cleavage and polyadenylation specificity factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    cleavage and polyadenylation specificity factor complex subunit Yth1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      510410..511364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018362.3 → NP_592962.1  cleavage and polyadenylation specificity factor complex subunit Yth1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592962.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UTD1
      Conserved Domains (3) summary
      smart00356
      Location:131 → 156
      ZnF_C3H1; zinc finger
      COG5084
      Location:1 → 170
      YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]
      pfam00642
      Location:77 → 101
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials