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    ubi4 protein modifier, ubiquitin [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541030, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ubi4
    Official Full Name
    protein modifier, ubiquitin
    Primary source
    PomBase:SPBC337.08c
    Locus tag
    SPOM_SPBC337.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ubi4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1044271..1045592, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein Cwf15 Neighboring gene carboxypeptidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Erg28 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The polyubiquitin gene is essential for meiosis in fission yeast. Okazaki K, et al. Exp Cell Res, 2000 Jan 10. PMID 10623474
    2. Crystal structure of the Thr316Ala mutant of a yeast JAMM deubiquitinase: implication of active-site loop dynamics in catalysis. Shrestha R, et al. Acta Crystallogr F Struct Biol Commun, 2021 Jun 1. PMID 34100774, Free PMC Article
    3. Ubiquitin-PCNA fusion as a mimic for mono-ubiquitinated PCNA in Schizosaccharomyces pombe. Ramasubramanyan S, et al. DNA Repair (Amst), 2010 Jul 1. PMID 20452294
    4. Click synthesis of ubiquitin dimer analogs to interrogate linkage-specific UBA domain binding. Weikart ND, et al. Chem Commun (Camb), 2012 Jan 7. PMID 22095407
    5. Insights into the mechanism of deubiquitination by JAMM deubiquitinases from cocrystal structures of the enzyme with the substrate and product. Shrestha RK, et al. Biochemistry, 2014 May 20. PMID 24787148, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables enzyme inhibitor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein tag activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in meiotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in modification-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein modifier, ubiquitin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1044271..1045592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021316.3 → NP_595409.1  protein modifier, ubiquitin [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595409.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P0CG72
      Conserved Domains (2) summary
      cd01803
      Location:77 → 152
      Ubiquitin; Ubiquitin
      smart00213
      Location:1 → 72
      UBQ; Ubiquitin homologues
    Nucleotide Protein
    Heading Accession and Version

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