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    cdk11 Cdk11-cyclinL compex kinase subunit Cdk11 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540799, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cdk11
    Official Full Name
    Cdk11-cyclinL compex kinase subunit Cdk11
    Primary source
    PomBase:SPBC18H10.15
    Locus tag
    SPOM_SPBC18H10.15
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ppk23
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    Genomic context

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    See cdk11 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (1794981..1796679)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 40S ribosomal protein uS9 Neighboring gene ncRNA Neighboring gene vacuolar membrane cation-chloride cotransporter Vhc1 Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein mL67

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cdk11-cyclinL controls the assembly of the RNA polymerase II mediator complex. Drogat J, et al. Cell Rep, 2012 Nov 29. PMID 23122962
    2. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables RNA polymerase II CTD heptapeptide repeat S2 kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT enables RNA polymerase II CTD heptapeptide repeat S5 kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of mediator complex assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signaling NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cyclin-dependent protein kinase holoenzyme complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cdk11-cyclinL compex kinase subunit Cdk11

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1794981..1796679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021637.3 → NP_595739.1  Cdk11-cyclinL compex kinase subunit Cdk11 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595739.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60145
      Conserved Domains (2) summary
      cd07843
      Location:68 → 359
      STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1
      PLN00009
      Location:71 → 361
      PLN00009; cyclin-dependent kinase A; Provisional
    Nucleotide Protein
    Heading Accession and Version

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