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    pdf1 palmitoyl protein thioesterase/ dolichol pyrophosphate phosphatase fusion protein Pdf1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540904, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pdf1
    Official Full Name
    palmitoyl protein thioesterase/ dolichol pyrophosphate phosphatase fusion protein Pdf1
    Primary source
    PomBase:SPBC530.12c
    Locus tag
    SPOM_SPBC530.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See pdf1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (820804..823168, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tRNA-Glu Neighboring gene ncRNA Neighboring gene Lsk1 associated cyclin Neighboring gene SR protein-specific kinase Dsk1 Neighboring gene spermidine family transporter Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. pdf1, a palmitoyl protein thioesterase 1 Ortholog in Schizosaccharomyces pombe: a yeast model of infantile Batten disease. Cho SK, et al. Eukaryot Cell, 2004 Apr. PMID 15075260, Free PMC Article
    2. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article
    3. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables dolichyldiphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables palmitoyl-(protein) hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane lipid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    palmitoyl protein thioesterase/ dolichol pyrophosphate phosphatase fusion protein Pdf1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      820804..823168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021232.3 → NP_595325.2  palmitoyl protein thioesterase/ dolichol pyrophosphate phosphatase fusion protein Pdf1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595325.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59747
      Conserved Domains (3) summary
      COG0671
      Location:406 → 578
      PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
      cd03382
      Location:415 → 568
      PAP2_dolichyldiphosphatase; PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is ...
      cl21494
      Location:45 → 314
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version

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