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    gas1 1,3-beta-glucanosyltransferase Gas1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542584, updated on 18-Sep-2024

    Summary

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    Official Symbol
    gas1
    Official Full Name
    1,3-beta-glucanosyltransferase Gas1
    Primary source
    PomBase:SPAC19B12.02c
    Locus tag
    SPOM_SPAC19B12.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See gas1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4878579..4880740, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene TTC27 family TPR repeat-containing protein Neighboring gene ncRNA Neighboring gene protein Cmc4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. gas1 mutation extends chronological lifespan via Pmk1 and Sty1 MAPKs in Schizosaccharomyces pombe. Imai Y, et al. Biosci Biotechnol Biochem, 2020 Feb. PMID 31601154
    2. β(1,3)-glucanosyl-transferase activity is essential for cell wall integrity and viability of Schizosaccharomyces pombe. de Medina-Redondo M, et al. PLoS One, 2010 Nov 18. PMID 21124977, Free PMC Article
    3. Mass spectrometric identification of covalently bound cell wall proteins from the fission yeast Schizosaccharomyces pombe. de Groot PW, et al. Yeast, 2007 Apr. PMID 17230583
    4. Genome-wide identification of fungal GPI proteins. De Groot PW, et al. Yeast, 2003 Jul 15. PMID 12845604
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. propose that the gas1-287 mutation causes longevity as the similar mechanism as cell wall stress depending on Pmk1 and Sty1 MAPK pathways
      Title: gas1 mutation extends chronological lifespan via Pmk1 and Sty1 MAPKs in Schizosaccharomyces pombe.
    2. Data show that gas1Delta mutants can only grow in osmotically supported media, while gas2p and gas5p play a minor role in cell wall construction.
      Title: β(1,3)-glucanosyl-transferase activity is essential for cell wall integrity and viability of Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 1,3-beta-glucanosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 1,3-beta-glucanosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in external side of plasma membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in new growing cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in old growing cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1,3-beta-glucanosyltransferase Gas1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4878579..4880740 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020192.3 → NP_594765.1  1,3-beta-glucanosyltransferase Gas1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594765.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78853, Q9P378
      Conserved Domains (2) summary
      pfam07983
      Location:375 → 446
      X8; X8 domain
      cl23725
      Location:13 → 325
      Glyco_hydro_1; Glycosyl hydrolase family 1
    Nucleotide Protein
    Heading Accession and Version

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