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    pdp1 PWWP domain protein Pdp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540354, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pdp1
    Official Full Name
    PWWP domain protein Pdp1
    Primary source
    PomBase:SPBC29A3.13
    Locus tag
    SPOM_SPBC29A3.13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See pdp1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2059635..2062284, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene AAA family ATPase Gcn20 Neighboring gene F1-ATPase subunit H Neighboring gene carboxylic acid transporter Neighboring gene ncRNA Neighboring gene 40S ribosomal protein uS4 Neighboring gene ncRNA Neighboring gene telomerase reverse transcriptase 1 protein Trt1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA. Qiu Y, et al. Biochem J, 2012 Mar 15. PMID 22150589
    2. Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein. Wang Y, et al. Mol Cell, 2009 Feb 27. PMID 19250904, Free PMC Article
    3. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article
    4. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
    5. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables H4K20me3 modified histone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables histone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables methylated histone binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling ISM
    Inferred from Sequence Model
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of NuA3 histone acetyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    PWWP domain protein Pdp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2059635..2062284 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021745.3 → NP_595841.1  PWWP domain protein Pdp1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595841.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59676, Q9USE8
      Conserved Domains (1) summary
      cd05840
      Location:50 → 140
      SPBC215_ISWI_like; The PWWP domain is a component of the S. pombe hypothetical protein SPBC215, as well as ISWI complex protein 4. The ISWI (imitation switch) proteins are ATPases responsible for chromatin remodeling in eukaryotes, and SPBC215 is proposed to also bind ...
    Nucleotide Protein
    Heading Accession and Version

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