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    chc1 clathrin heavy chain Chc1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542078, updated on 18-Sep-2024

    Summary

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    Official Symbol
    chc1
    Official Full Name
    clathrin heavy chain Chc1
    Primary source
    PomBase:SPAC26A3.05
    Locus tag
    SPOM_SPAC26A3.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See chc1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (3339090..3344445)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene 60S ribosomal protein eL20 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene S-adenosylmethionine-dependent methyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of cell wall synthesis by the clathrin light chain is essential for viability in Schizosaccharomyces pombe. de León N, et al. PLoS One, 2013. PMID 23977061, Free PMC Article
    2. Studies on the roles of clathrin-mediated membrane trafficking and zinc transporter Cis4 in the transport of GPI-anchored proteins in fission yeast. Jaiseng W, et al. PLoS One, 2012. PMID 22848669, Free PMC Article
    3. Quantitative analysis of the mechanism of endocytic actin patch assembly and disassembly in fission yeast. Sirotkin V, et al. Mol Biol Cell, 2010 Aug 15. PMID 20587778, Free PMC Article
    4. The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring. Roberts-Galbraith RH, et al. J Cell Biol, 2009 Jan 12. PMID 19139265, Free PMC Article
    5. SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Singh NS, et al. Curr Biol, 2011 Dec 6. PMID 22119525, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables clathrin light chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural molecule activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to endosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in clathrin-dependent endocytosis NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in endosome to plasma membrane protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in receptor-mediated endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cortical patch IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in actin cortical patch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of clathrin coat of trans-Golgi network vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of clathrin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in clathrin-coated pit IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm HDA PubMed 

    General protein information

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    Preferred Names
    clathrin heavy chain Chc1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3339090..3344445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019572.3 → NP_594148.1  clathrin heavy chain Chc1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594148.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10161
      Conserved Domains (4) summary
      smart00299
      Location:1270 → 1411
      CLH; Clathrin heavy chain repeat homology
      pfam01394
      Location:254 → 286
      Clathrin_propel; Clathrin propeller repeat
      pfam09268
      Location:329 → 352
      Clathrin-link; Clathrin, heavy-chain linker
      pfam13838
      Location:354 → 419
      Clathrin_H_link; Clathrin-H-link
    Nucleotide Protein
    Heading Accession and Version

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