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    dlp1 decaprenyl diphosphate synthase subunit 2 Dlp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542608, updated on 18-Sep-2024

    Summary

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    Official Symbol
    dlp1
    Official Full Name
    decaprenyl diphosphate synthase subunit 2 Dlp1
    Primary source
    PomBase:SPAC19G12.12
    Locus tag
    SPOM_SPAC19G12.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See dlp1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4068599..4069929)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein erh1 Neighboring gene ubiquinone biosynthesis protein Coq9 Neighboring gene ncRNA Neighboring gene protein Poz1 Neighboring gene ncRNA Neighboring gene 1-phosphatidylinositol-4-phosphate 5-kinase Its3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast decaprenyl diphosphate synthase consists of Dps1 and the newly characterized Dlp1 protein in a novel heterotetrameric structure. Saiki R, et al. Eur J Biochem, 2003 Oct. PMID 14519123
    2. A subunit of decaprenyl diphosphate synthase stabilizes octaprenyl diphosphate synthase in Escherichia coli by forming a high-molecular weight complex. Cui TZ, et al. FEBS Lett, 2010 Feb 19. PMID 20051244
    3. Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humans. Hayashi K, et al. PLoS One, 2014. PMID 24911838, Free PMC Article
    4. Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans. Saiki R, et al. FEBS J, 2005 Nov. PMID 16262699
    5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that expression of either dlp1 or dps1 recovered the thermo-sensitive growth of an E. coli ispB(R321A) mutant and restored IspB activity and production of Coenzyme Q-8.
      Title: A subunit of decaprenyl diphosphate synthase stabilizes octaprenyl diphosphate synthase in Escherichia coli by forming a high-molecular weight complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to all-trans-decaprenyl-diphosphate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables prenyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in isoprenoid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in isoprenoid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ubiquinone biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquinone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heterotetrameric polyprenyl diphosphate synthase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of polyprenyl diphosphate synthase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    decaprenyl diphosphate synthase subunit 2 Dlp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4068599..4069929
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019856.3 → NP_594427.1  decaprenyl diphosphate synthase subunit 2 Dlp1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594427.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13851
      Conserved Domains (1) summary
      COG0142
      Location:2 → 294
      IspA; Geranylgeranyl pyrophosphate synthase [Coenzyme transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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