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    ATP25 Atp25p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855123, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ATP25
    Official Full Name
    Atp25p
    Primary source
    SGD:S000004704
    Locus tag
    YMR098C
    See related
    AllianceGenome:SGD:S000004704; FungiDB:YMR098C; VEuPathDB:YMR098C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in mRNA stabilization and mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ATP25 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (460771..462609, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene pyridoxine biosynthesis protein SNZ1 Neighboring gene putative GTPase MTG1 Neighboring gene tRNA-Asp Neighboring gene glucose-6-phosphate 1-epimerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATP25, a new nuclear gene of Saccharomyces cerevisiae required for expression and assembly of the Atp9p subunit of mitochondrial ATPase. Zeng X, et al. Mol Biol Cell, 2008 Apr. PMID 18216280, Free PMC Article
    2. Proteomic profiling of the mitochondrial ribosome identifies Atp25 as a composite mitochondrial precursor protein. Woellhaf MW, et al. Mol Biol Cell, 2016 Oct 15. PMID 27582385, Free PMC Article
    3. Spatial orchestration of mitochondrial translation and OXPHOS complex assembly. Stoldt S, et al. Nat Cell Biol, 2018 May. PMID 29662179
    4. The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress. Backes S, et al. Cell Rep, 2021 Apr 6. PMID 33826901, Free PMC Article
    5. The ribosome receptors Mrx15 and Mba1 jointly organize cotranslational insertion and protein biogenesis in mitochondria. Möller-Hergt BV, et al. Mol Biol Cell, 2018 Oct 1. PMID 30091672, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. report a new nuclear gene, designated ATP25 (reading frame YMR098C on chromosome XIII), required for expression of Atp9p (subunit 9) of the mitochondrial proton translocating ATPase
      Title: ATP25, a new nuclear gene of Saccharomyces cerevisiae required for expression and assembly of the Atp9p subunit of mitochondrial ATPase.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA stabilization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA stabilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial gene expression IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial proton-transporting ATP synthase complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Atp25p
    NP_013816.1
    • Protein that associates with mitochondrial ribosome; required for the stability of Oli1p (Atp9p) mRNA; also required for the Oli1p ring formation; YMR098C is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      460771..462609 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182598.1 → NP_013816.1  TPA: Atp25p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013816.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3LLY9, C7GL28, C8ZEV0, D6VZS1, Q03153
      UniProtKB/TrEMBL
      G2WKE6, N1NXB4
      Conserved Domains (2) summary
      pfam02410
      Location:105 → 246
      RsfS; Ribosomal silencing factor during starvation
      pfam13929
      Location:303 → 594
      mRNA_stabil; mRNA stabilisation
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03153.1

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