QDR3 Qdr3p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: QDR3
Official Full Name: Qdr3p
Primary source: SGD:S000000247
Locus tag: YBR043C
See related: AllianceGenome:SGD:S000000247; FungiDB:YBR043C; VEuPathDB:YBR043C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: AQR2
Summary: Enables polyamine transmembrane transporter activity and threonine efflux transmembrane transporter activity. Involved in amino acid export across plasma membrane; ascospore wall assembly; and intracellular polyamine homeostasis. Located in cell periphery. Is active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome II - NC_001134.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables efflux transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables polyamine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables polyamine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables threonine efflux transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in amino acid export across plasma membrane	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ascospore wall assembly	IGI Inferred from Genetic Interaction more info	PubMed
involved_in intracellular polyamine homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular polyamine homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in polyamine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in threonine transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cell periphery	HDA more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

NP_009599.2

Multidrug transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; has a role in polyamine homeostasis; involved in spore wall asembly; sequence similarity to DTR1 and QDR1, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin

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The following sections contain reference sequences that belong to a specific genome build. Explain