U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CEACAM19 CEA cell adhesion molecule 19 [ Homo sapiens (human) ]

    Gene ID: 56971, updated on 9-Dec-2024

    Summary

    Official Symbol
    CEACAM19provided by HGNC
    Official Full Name
    CEA cell adhesion molecule 19provided by HGNC
    Primary source
    HGNC:HGNC:31951
    See related
    Ensembl:ENSG00000186567 MIM:606691; AllianceGenome:HGNC:31951
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CEAL1; CEACM19
    Summary
    Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in skin (RPKM 5.4), testis (RPKM 2.3) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CEACAM19 in Genome Data Viewer
    Location:
    19q13.31
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (44665860..44684355)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (47490642..47509104)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (45169128..45187627)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:45118285-45118786 Neighboring gene immunoglobulin superfamily member 23 Neighboring gene Sharpr-MPRA regulatory region 2639 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10734 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14764 Neighboring gene MPRA-validated peak3503 silencer Neighboring gene PVR cell adhesion molecule Neighboring gene microRNA 4531 Neighboring gene uncharacterized LOC107985306 Neighboring gene Sharpr-MPRA regulatory region 3873 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:45192479-45192980 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:45192981-45193480 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14765 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:45199988-45200593 Neighboring gene CEACAM16, CEACAM19 and PVR antisense RNA 1 Neighboring gene CEA cell adhesion molecule 16, tectorial membrane component

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC105097

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cell adhesion molecule CEACAM19
    Names
    carcinoembryonic antigen related cell adhesion molecule 19
    carcinoembryonic antigen-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127893.3NP_001121365.1  cell adhesion molecule CEACAM19 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001121365.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the shorter protein (isoform 1).
      Source sequence(s)
      AC243964
      Consensus CDS
      CCDS46108.1
      UniProtKB/TrEMBL
      A0A158VUY4
      Related
      ENSP00000351627.4, ENST00000358777.10
      Conserved Domains (2) summary
      cd00096
      Location:4244
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:36140
      Ig; Immunoglobulin domain
    2. NM_001389722.1NP_001376651.1  cell adhesion molecule CEACAM19 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC243964
      Consensus CDS
      CCDS46108.1
      UniProtKB/TrEMBL
      A0A158VUY4
      Conserved Domains (2) summary
      cd00096
      Location:4244
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:36140
      Ig; Immunoglobulin domain
    3. NM_020219.5NP_064604.2  cell adhesion molecule CEACAM19 isoform 2 precursor

      See identical proteins and their annotated locations for NP_064604.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is longer and has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AC243964
      Consensus CDS
      CCDS12641.1
      UniProtKB/Swiss-Prot
      Q5XJ15, Q7Z692, Q7Z693
      UniProtKB/TrEMBL
      A0A158VVV8
      Related
      ENSP00000384887.3, ENST00000403660.3
      Conserved Domains (1) summary
      cl11960
      Location:36140
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      44665860..44684355
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      47490642..47509104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)