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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_007013.4 → NP_008944.1 NEDD4-like E3 ubiquitin-protein ligase WWP1
See identical proteins and their annotated locations for NP_008944.1
Status: VALIDATED
- Source sequence(s)
-
AC103760, AC103817, AW137654, AY043361, BC036065, BM664090
- Consensus CDS
-
CCDS6242.1
- UniProtKB/Swiss-Prot
- O00307, Q5YLC1, Q96BP4, Q9H0M0
- UniProtKB/TrEMBL
-
A8K9T5
- Related
- ENSP00000427793.1, ENST00000517970.6
- Conserved Domains (2) summary
-
- cd04021
Location:17 → 140
- C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase
- COG5021
Location:307 → 922
- HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000008.11 Reference GRCh38.p14 Primary Assembly
- Range
-
86342547..86468503
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_024447056.2 → XP_024302824.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X3
- UniProtKB/TrEMBL
-
A8K9T5
- Conserved Domains (4) summary
-
- cd04021
Location:17 → 140
- C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase
- cd00078
Location:559 → 896
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
- cd00201
Location:499 → 528
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- pfam00397
Location:351 → 380
- WW; WW domain
-
XM_005250761.5 → XP_005250818.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2
- UniProtKB/TrEMBL
-
A8K9T5
- Conserved Domains (6) summary
-
- cd04021
Location:17 → 140
- C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase
- smart00119
Location:590 → 918
- HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
- cd00078
Location:567 → 919
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
- cd00201
Location:498 → 527
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- pfam00397
Location:350 → 379
- WW; WW domain
- pfam07010
Location:201 → 326
- Endomucin; Endomucin
-
XM_047421282.1 → XP_047277238.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X4
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_005250760.5 → XP_005250817.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1
See identical proteins and their annotated locations for XP_005250817.1
- UniProtKB/Swiss-Prot
- O00307, Q5YLC1, Q96BP4, Q9H0M0
- UniProtKB/TrEMBL
-
A8K9T5
- Related
- ENSP00000265428.4, ENST00000265428.4
- Conserved Domains (2) summary
-
- cd04021
Location:17 → 140
- C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase
- COG5021
Location:307 → 922
- HUL4; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
-
XM_017012994.3 → XP_016868483.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X3
- UniProtKB/TrEMBL
-
A8K9T5
- Conserved Domains (4) summary
-
- cd04021
Location:17 → 140
- C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase
- cd00078
Location:559 → 896
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
- cd00201
Location:499 → 528
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- pfam00397
Location:351 → 380
- WW; WW domain
-
XM_017012993.2 → XP_016868482.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2
- UniProtKB/TrEMBL
-
A8K9T5
- Conserved Domains (6) summary
-
- cd04021
Location:17 → 140
- C2_E3_ubiquitin_ligase; C2 domain present in E3 ubiquitin ligase
- smart00119
Location:590 → 918
- HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
- cd00078
Location:567 → 919
- HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
- cd00201
Location:498 → 527
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- pfam00397
Location:350 → 379
- WW; WW domain
- pfam07010
Location:201 → 326
- Endomucin; Endomucin
-
XM_047421283.1 → XP_047277239.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X4
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_047421285.1 → XP_047277241.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X6
-
XM_047421284.1 → XP_047277240.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X5
- UniProtKB/TrEMBL
-
A8K9T5
Alternate T2T-CHM13v2.0
Genomic
-
NC_060932.1 Alternate T2T-CHM13v2.0
- Range
-
87462833..87588744
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054359634.1 → XP_054215609.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X3
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_054359632.1 → XP_054215607.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_054359636.1 → XP_054215611.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X4
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_054359631.1 → XP_054215606.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1
- UniProtKB/Swiss-Prot
- O00307, Q5YLC1, Q96BP4, Q9H0M0
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_054359635.1 → XP_054215610.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X3
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_054359633.1 → XP_054215608.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X2
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_054359637.1 → XP_054215612.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X4
- UniProtKB/TrEMBL
-
A8K9T5
-
XM_054359639.1 → XP_054215614.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X6
-
XM_054359638.1 → XP_054215613.1 NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X5
- UniProtKB/TrEMBL
-
A8K9T5