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    Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 [ Mus musculus (house mouse) ]

    Gene ID: 66413, updated on 9-Dec-2024

    Summary

    Official Symbol
    Psmd6provided by MGI
    Official Full Name
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 6provided by MGI
    Primary source
    MGI:MGI:1913663
    See related
    Ensembl:ENSMUSG00000021737 AllianceGenome:MGI:1913663
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2400006A19Rik
    Summary
    Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of proteasome accessory complex. Is expressed in early conceptus. Orthologous to human PSMD6 (proteasome 26S subunit, non-ATPase 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 46.5), placenta adult (RPKM 44.7) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Psmd6 in Genome Data Viewer
    Location:
    14 A1; 14 7.08 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (8348818..8357578)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (14112185..14120945, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene casein kinase 2, alpha 1 polypeptide, pseudogene 1 Neighboring gene olfactory receptor family 2 subfamily T member 6 Neighboring gene ataxin 7 Neighboring gene STARR-seq mESC enhancer starr_35986 Neighboring gene predicted gene, 53821 Neighboring gene THO complex 7 Neighboring gene predicted gene 11100

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    26S proteasome non-ATPase regulatory subunit 6
    Names
    26S proteasome regulatory subunit RPN7
    26S proteasome regulatory subunit S10
    p42A
    proteasome, 26S, non-ATPase regulatory subunit 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025550.3NP_079826.2  26S proteasome non-ATPase regulatory subunit 6

      See identical proteins and their annotated locations for NP_079826.2

      Status: VALIDATED

      Source sequence(s)
      AC116479
      Consensus CDS
      CCDS26824.1
      UniProtKB/Swiss-Prot
      Q99JI4, Q9CWZ1
      Related
      ENSMUSP00000022256.4, ENSMUST00000022256.5
      Conserved Domains (1) summary
      COG5187
      Location:15382
      RPN7; 26S proteasome regulatory complex component, contains PCI domain [Posttranslational modification, protein turnover, chaperones]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      8348818..8357578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)