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    TMEM267 transmembrane protein 267 [ Homo sapiens (human) ]

    Gene ID: 64417, updated on 27-Nov-2024

    Summary

    Official Symbol
    TMEM267provided by HGNC
    Official Full Name
    transmembrane protein 267provided by HGNC
    Primary source
    HGNC:HGNC:26139
    See related
    Ensembl:ENSG00000151881 AllianceGenome:HGNC:26139
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C5orf28
    Summary
    Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in thyroid (RPKM 13.3), prostate (RPKM 2.9) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See TMEM267 in Genome Data Viewer
    Location:
    5p12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (43444252..43484387, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (43697085..43737220, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (43444354..43484489, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P1-like Neighboring gene C-C motif chemokine ligand 28 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22538 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15993 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15994 Neighboring gene Sharpr-MPRA regulatory region 10963 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:43483998-43484841 Neighboring gene C5orf34 antisense RNA 1 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_85282 Neighboring gene chromosome 5 open reading frame 34 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 19 Neighboring gene uncharacterized LOC124900190 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22540

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ21657, MGC90226, MGC149524

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 267
    Names
    transmembrane protein C5orf28

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001377394.1NP_001364323.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
      Related
      ENSP00000422881.1, ENST00000512085.5
    2. NM_001377395.1NP_001364324.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
    3. NM_001377396.1NP_001364325.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
    4. NM_001377397.1NP_001364326.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
    5. NM_001377398.1NP_001364327.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
    6. NM_001377399.1NP_001364328.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
    7. NM_001377400.1NP_001364329.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
    8. NM_001377401.1NP_001364330.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
      Related
      ENSP00000424720.1, ENST00000506860.1
    9. NM_001377402.1NP_001364331.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
    10. NM_001377403.1NP_001364332.1  transmembrane protein 267

      Status: VALIDATED

      Source sequence(s)
      AC025457
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
      Related
      ENSP00000426067.1, ENST00000500337.6
    11. NM_022483.5NP_071928.2  transmembrane protein 267

      See identical proteins and their annotated locations for NP_071928.2

      Status: VALIDATED

      Source sequence(s)
      AC025457, DA028175, DA035926
      Consensus CDS
      CCDS3945.1
      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
      Related
      ENSP00000380270.3, ENST00000397080.8

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      43444252..43484387 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047417517.1XP_047273473.1  transmembrane protein 267 isoform X1

      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
    2. XM_011514075.4XP_011512377.1  transmembrane protein 267 isoform X1

      See identical proteins and their annotated locations for XP_011512377.1

      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
      UniProtKB/TrEMBL
      D6RAV6
    3. XM_047417516.1XP_047273472.1  transmembrane protein 267 isoform X1

      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      43697085..43737220 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054353126.1XP_054209101.1  transmembrane protein 267 isoform X1

      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
    2. XM_054353125.1XP_054209100.1  transmembrane protein 267 isoform X1

      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2
    3. XM_054353124.1XP_054209099.1  transmembrane protein 267 isoform X1

      UniProtKB/Swiss-Prot
      B2RDA6, Q0VDI3, Q9H6Z2