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    ACTL10 actin like 10 [ Homo sapiens (human) ]

    Gene ID: 170487, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ACTL10provided by HGNC
    Official Full Name
    actin like 10provided by HGNC
    Primary source
    HGNC:HGNC:16127
    See related
    Ensembl:ENSG00000288649 AllianceGenome:HGNC:16127
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    dJ63M2.2; C20orf134
    Orthologs
    mouse all
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    Genomic context

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    See ACTL10 in Genome Data Viewer
    Location:
    20q11.22
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (33666943..33668525)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (35393474..35395056)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (32254749..32256331)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12814 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12813 Neighboring gene CBFA2/RUNX1 partner transcriptional co-repressor 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32104950-32105714 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:32115920-32116420 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:32116421-32116921 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:32118677-32119177 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:32121705-32122204 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:32124101-32124819 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17735 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:32144891-32145546 Neighboring gene Sharpr-MPRA regulatory region 10659 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32156001-32156927 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:32169053-32169552 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32169790-32170374 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32170375-32170958 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:32175233-32175732 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12815 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32240942-32241530 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:32244101-32244601 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32250716-32251654 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32251655-32252591 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17738 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12817 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17739 Neighboring gene chromosome 20 open reading frame 144 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32259897-32260446 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32260995-32261542 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32261543-32262090 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:32262761-32263261 Neighboring gene N-terminal EF-hand calcium binding protein 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32267321-32267940 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:32267941-32268559 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12819 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12820 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr20:32287672-32288382 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr20:32288383-32289094 Neighboring gene E2F transcription factor 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17741 Neighboring gene peroxisomal membrane protein 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The DNA sequence and comparative analysis of human chromosome 20. Deloukas P, et al. Nature, 2001 Dec 20-27. PMID 11780052
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Homology

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    actin-like protein 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024675.2 → NP_001019846.1  actin-like protein 10

      See identical proteins and their annotated locations for NP_001019846.1

      Status: VALIDATED

      Source sequence(s)
      AW006704, BC137111
      Consensus CDS
      CCDS33463.1
      UniProtKB/Swiss-Prot
      B9EH76, Q5JWF8
      Related
      ENSP00000504425.1, ENST00000677665.1
      Conserved Domains (1) summary
      cl17037
      Location:2 → 237
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      33666943..33668525
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      35393474..35395056
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5JWF8.1 GenPept UniProtKB/Swiss-Prot:Q5JWF8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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