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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001042558.2 → NP_001036023.1 apoptotic protease-activating factor 1 isoform 1
See identical proteins and their annotated locations for NP_001036023.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) has an additional segment in the 5' UTR, compared to variant 2. Variants 1 and 2 both encode the same isoform (1).
- Source sequence(s)
-
AC138719, AC140410
- Consensus CDS
-
CCDS36030.1
- UniProtKB/Swiss-Prot
- A2RRK8, O88879
- UniProtKB/TrEMBL
-
Q5DU30
- Related
- ENSMUSP00000020157.7, ENSMUST00000020157.13
- Conserved Domains (5) summary
-
- cd00200
Location:607 → 910
- WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
- cd08323
Location:7 → 92
- CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
- sd00039
Location:623 → 655
- 7WD40; WD40 repeat [structural motif]
- pfam00931
Location:129 → 374
- NB-ARC; NB-ARC domain
- pfam17908
Location:453 → 587
- APAF1_C; APAF-1 helical domain
-
NM_001282947.2 → NP_001269876.1 apoptotic protease-activating factor 1 isoform 2
See identical proteins and their annotated locations for NP_001269876.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks an in-frame segment in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
- Source sequence(s)
-
AC138719, AC140410
- Consensus CDS
-
CCDS70095.1
- UniProtKB/TrEMBL
- G3XA09, Q5DU30
- Related
- ENSMUSP00000124134.2, ENSMUST00000162618.8
- Conserved Domains (5) summary
-
- COG2319
Location:642 → 1027
- WD40; WD40 repeat [General function prediction only]
- cd00200
Location:596 → 899
- WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
- cd08323
Location:7 → 92
- CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
- pfam00931
Location:118 → 403
- NB-ARC; NB-ARC domain
- sd00039
Location:612 → 644
- 7WD40; WD40 repeat [structural motif]
-
NM_001428359.1 → NP_001415288.1 apoptotic protease-activating factor 1 isoform 3
Status: VALIDATED
- Source sequence(s)
-
AC138719, AC140410
- UniProtKB/TrEMBL
-
Q5DU30
-
NM_001428360.1 → NP_001415289.1 apoptotic protease-activating factor 1 isoform 3
Status: VALIDATED
- Source sequence(s)
-
AC138719, AC140410
- UniProtKB/TrEMBL
-
Q5DU30
-
NM_009684.3 → NP_033814.2 apoptotic protease-activating factor 1 isoform 1
See identical proteins and their annotated locations for NP_033814.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) encodes the longest isoform (1). Variants 1 and 2 both encode the same isoform (1).
- Source sequence(s)
-
AC138719, AC140410
- Consensus CDS
-
CCDS36030.1
- UniProtKB/Swiss-Prot
- A2RRK8, O88879
- UniProtKB/TrEMBL
-
Q5DU30
- Related
- ENSMUSP00000125291.2, ENSMUST00000159110.8
- Conserved Domains (5) summary
-
- cd00200
Location:607 → 910
- WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
- cd08323
Location:7 → 92
- CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
- sd00039
Location:623 → 655
- 7WD40; WD40 repeat [structural motif]
- pfam00931
Location:129 → 374
- NB-ARC; NB-ARC domain
- pfam17908
Location:453 → 587
- APAF1_C; APAF-1 helical domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000076.7 Reference GRCm39 C57BL/6J
- Range
-
90825173..90918688 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_036155560.1 → XP_036011453.1 apoptotic protease-activating factor 1 isoform X1
- Conserved Domains (5) summary
-
- cd00200
Location:607 → 910
- WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
- cd08323
Location:7 → 92
- CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
- sd00039
Location:623 → 655
- 7WD40; WD40 repeat [structural motif]
- pfam00931
Location:129 → 374
- NB-ARC; NB-ARC domain
- pfam17908
Location:453 → 587
- APAF1_C; APAF-1 helical domain
-
XM_036155561.1 → XP_036011454.1 apoptotic protease-activating factor 1 isoform X1
- Conserved Domains (5) summary
-
- cd00200
Location:607 → 910
- WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
- cd08323
Location:7 → 92
- CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
- sd00039
Location:623 → 655
- 7WD40; WD40 repeat [structural motif]
- pfam00931
Location:129 → 374
- NB-ARC; NB-ARC domain
- pfam17908
Location:453 → 587
- APAF1_C; APAF-1 helical domain
-
XM_036155562.1 → XP_036011455.1 apoptotic protease-activating factor 1 isoform X2
- Conserved Domains (3) summary
-
- cd00200
Location:148 → 451
- WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
- sd00039
Location:164 → 196
- 7WD40; WD40 repeat [structural motif]
- pfam17908
Location:1 → 128
- APAF1_C; APAF-1 helical domain
RNA
-
XR_004936065.1 RNA Sequence