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    H1f7 H1.7 linker histone [ Mus musculus (house mouse) ]

    Gene ID: 70069, updated on 9-Dec-2024

    Summary

    Official Symbol
    H1f7provided by MGI
    Official Full Name
    H1.7 linker histoneprovided by MGI
    Primary source
    MGI:MGI:1917319
    See related
    Ensembl:ENSMUSG00000048077 AllianceGenome:MGI:1917319
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H1-7; H1.7; H1t2; H1fnt; Hanp1; mH1t2; 1700026P10Rik
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. This gene encodes a testis specific protein that is required for spermatogenesis and male fertility. [provided by RefSeq, Oct 2015]
    Orthologs
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    Genomic context

    See H1f7 in Genome Data Viewer
    Location:
    15 F1; 15 54.26 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98153863..98155188, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (98255982..98257307, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 10 subfamily AD member 1 Neighboring gene olfactory receptor family 10 subfamily AD member 1B Neighboring gene STARR-seq mESC enhancer starr_39658 Neighboring gene predicted gene, 33967 Neighboring gene STARR-seq mESC enhancer starr_39659 Neighboring gene zinc finger protein 641 Neighboring gene olfactory receptor family 8 subfamily S member 16

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    testis-specific H1 histone
    Names
    H1 histone family, member N, testis-specific
    expressed in haploid spermatids during spermiogenesis, specifically at the apical pole of round and elongating spermatids
    haploid germ cell-specific nuclear protein 1
    histone H1.7
    histone H1t2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027304.2NP_081580.2  testis-specific H1 histone

      See identical proteins and their annotated locations for NP_081580.2

      Status: REVIEWED

      Source sequence(s)
      AB016273, AC105982, BC052363
      Consensus CDS
      CCDS49721.1
      UniProtKB/Swiss-Prot
      Q5GKZ6, Q5RKV2, Q8CJI4, Q9CVV3
      Related
      ENSMUSP00000127616.2, ENSMUST00000060855.7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      98153863..98155188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)