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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029641.1 RefSeqGene
- Range
-
5018..107845
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001243146.2 → NP_001230075.1 nuclear valosin-containing protein-like isoform 3
See identical proteins and their annotated locations for NP_001230075.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks three alternate coding exons in the 5' coding region, uses a downstream initiation codon, and contains an alternate in-frame exon, compared to variant 1. The resulting protein (isoform 3) is shorter and has a distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AC092809, AK297396, BP284587, BU683548
- Consensus CDS
-
CCDS58062.1
- UniProtKB/Swiss-Prot
-
O15381
- Related
- ENSP00000341362.4, ENST00000340871.8
- Conserved Domains (3) summary
-
- COG0464
Location:68 → 663
- SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
- pfam00004
Location:429 → 559
- AAA; ATPase family associated with various cellular activities (AAA)
- cl21455
Location:409 → 445
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001243147.2 → NP_001230076.1 nuclear valosin-containing protein-like isoform 4
See identical proteins and their annotated locations for NP_001230076.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.
- Source sequence(s)
-
AC092809, AK298244, BP284587, BU683548
- Consensus CDS
-
CCDS58063.1
- UniProtKB/TrEMBL
-
B4DLM8
- Related
- ENSP00000417826.1, ENST00000469075.5
- Conserved Domains (5) summary
-
- COG0464
Location:193 → 761
- SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
- pfam00004
Location:527 → 657
- AAA; ATPase family associated with various cellular activities (AAA)
- pfam16725
Location:2 → 72
- Nucleolin_bd; Nucleolin binding domain
- cl11522
Location:75 → 125
- Tom22; Mitochondrial import receptor subunit Tom22
- cl21455
Location:507 → 543
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_002533.4 → NP_002524.2 nuclear valosin-containing protein-like isoform 1
See identical proteins and their annotated locations for NP_002524.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1, also known as NVL.2 or the major isoform).
- Source sequence(s)
-
AC092809, AK293923, BP284587, BU683548, U68140
- Consensus CDS
-
CCDS1541.1
- UniProtKB/Swiss-Prot
- B4DMC4, B4DP98, O15381, Q96EM7
- UniProtKB/TrEMBL
-
B4DLM8
- Related
- ENSP00000281701.6, ENST00000281701.11
- Conserved Domains (4) summary
-
- COG0464
Location:284 → 852
- SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
- pfam00004
Location:618 → 748
- AAA; ATPase family associated with various cellular activities (AAA)
- pfam16725
Location:2 → 72
- Nucleolin_bd; Nucleolin binding domain
- cl21455
Location:598 → 634
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_206840.3 → NP_996671.1 nuclear valosin-containing protein-like isoform 2
See identical proteins and their annotated locations for NP_996671.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate exon and uses a downstream start codon compared to variant 1. The resulting protein (isoform 2, also known as NVL.1 or the minor isoform) is shorter and has a distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AC092809, AK293923, BP284587, BU683548, U78772
- Consensus CDS
-
CCDS1542.1
- UniProtKB/TrEMBL
-
B4DLM8
- Related
- ENSP00000375747.2, ENST00000391875.6
- Conserved Domains (1) summary
-
- cl27568
Location:137 → 750
- TIP49; TIP49 C-terminus
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
224227345..224330172 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017001383.2 → XP_016856872.1 nuclear valosin-containing protein-like isoform X5
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_011544196.1 → XP_011542498.1 nuclear valosin-containing protein-like isoform X4
- UniProtKB/TrEMBL
-
B4DLM8
- Conserved Domains (4) summary
-
- COG0464
Location:284 → 879
- SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
- pfam00004
Location:645 → 775
- AAA; ATPase family associated with various cellular activities (AAA)
- pfam16725
Location:2 → 72
- Nucleolin_bd; Nucleolin binding domain
- cl21455
Location:625 → 661
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
XM_017001379.2 → XP_016856868.1 nuclear valosin-containing protein-like isoform X2
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_017001378.2 → XP_016856867.1 nuclear valosin-containing protein-like isoform X1
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_047421613.1 → XP_047277569.1 nuclear valosin-containing protein-like isoform X7
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_017001380.3 → XP_016856869.1 nuclear valosin-containing protein-like isoform X3
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_047421631.1 → XP_047277587.1 nuclear valosin-containing protein-like isoform X12
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_047421621.1 → XP_047277577.1 nuclear valosin-containing protein-like isoform X10
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_047421618.1 → XP_047277574.1 nuclear valosin-containing protein-like isoform X8
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_017001384.2 → XP_016856873.1 nuclear valosin-containing protein-like isoform X6
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_047421637.1 → XP_047277593.1 nuclear valosin-containing protein-like isoform X14
- UniProtKB/TrEMBL
-
B4DQJ4
-
XM_047421635.1 → XP_047277591.1 nuclear valosin-containing protein-like isoform X13
- UniProtKB/TrEMBL
-
B4DQJ4
-
XM_047421626.1 → XP_047277582.1 nuclear valosin-containing protein-like isoform X11
- UniProtKB/TrEMBL
-
B4DQJ4
-
XM_017001385.3 → XP_016856874.1 nuclear valosin-containing protein-like isoform X9
- UniProtKB/TrEMBL
-
B4DLM8
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
223416266..223519053 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054336810.1 → XP_054192785.1 nuclear valosin-containing protein-like isoform X5
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336809.1 → XP_054192784.1 nuclear valosin-containing protein-like isoform X4
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336807.1 → XP_054192782.1 nuclear valosin-containing protein-like isoform X2
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336806.1 → XP_054192781.1 nuclear valosin-containing protein-like isoform X1
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336812.1 → XP_054192787.1 nuclear valosin-containing protein-like isoform X7
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336808.1 → XP_054192783.1 nuclear valosin-containing protein-like isoform X3
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336817.1 → XP_054192792.1 nuclear valosin-containing protein-like isoform X12
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336815.1 → XP_054192790.1 nuclear valosin-containing protein-like isoform X10
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336813.1 → XP_054192788.1 nuclear valosin-containing protein-like isoform X8
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336811.1 → XP_054192786.1 nuclear valosin-containing protein-like isoform X6
- UniProtKB/TrEMBL
-
B4DLM8
-
XM_054336819.1 → XP_054192794.1 nuclear valosin-containing protein-like isoform X14
- UniProtKB/TrEMBL
-
B4DQJ4
-
XM_054336818.1 → XP_054192793.1 nuclear valosin-containing protein-like isoform X13
- UniProtKB/TrEMBL
-
B4DQJ4
-
XM_054336816.1 → XP_054192791.1 nuclear valosin-containing protein-like isoform X11
- UniProtKB/TrEMBL
-
B4DQJ4
-
XM_054336814.1 → XP_054192789.1 nuclear valosin-containing protein-like isoform X9
- UniProtKB/TrEMBL
-
B4DLM8