These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
-
NM_000179.3 → NP_000170.1 DNA mismatch repair protein Msh6 isoform 1
See identical proteins and their annotated locations for NP_000170.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1).
- Source sequence(s)
-
BC071594, U54777
- Consensus CDS
-
CCDS1836.1
- UniProtKB/Swiss-Prot
- B4DF41, B4E3I4, F5H2F9, O43706, O43917, P52701, Q8TCX4, Q9BTB5
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
- Related
- ENSP00000234420.5, ENST00000234420.11
- Conserved Domains (7) summary
-
- cd05837
Location:88 → 195
- MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
- COG0249
Location:407 → 1336
- MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
- pfam01624
Location:407 → 525
- MutS_I; MutS domain I
- pfam05188
Location:538 → 692
- MutS_II; MutS domain II
- pfam05190
Location:932 → 1024
- MutS_IV; MutS family domain IV
- pfam05192
Location:739 → 827
- MutS_III; MutS domain III
- cl21455
Location:1091 → 1313
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001281492.2 → NP_001268421.1 DNA mismatch repair protein Msh6 isoform 2
See identical proteins and their annotated locations for NP_001268421.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site and lacks two exons in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
- Source sequence(s)
-
AK293921, BC071594
- Consensus CDS
-
CCDS62906.1
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
- Related
- ENSP00000446475.1, ENST00000540021.6
- Conserved Domains (6) summary
-
- COG0249
Location:277 → 1206
- MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
- pfam01624
Location:277 → 395
- MutS_I; MutS domain I
- pfam05188
Location:408 → 562
- MutS_II; MutS domain II
- pfam05190
Location:802 → 894
- MutS_IV; MutS family domain IV
- pfam05192
Location:609 → 697
- MutS_III; MutS domain III
- cl21455
Location:961 → 1183
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001281493.2 → NP_001268422.1 DNA mismatch repair protein Msh6 isoform 3
See identical proteins and their annotated locations for NP_001268422.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate in-frame exon and initiates translation at a downstream start codon compared to variant 1. The resulting protein (isoform 3) is shorter and has a distinct N-terminus compared to isoform 1. Variants 3 and 4 encode the same protein (isoform 3).
- Source sequence(s)
-
AC006509, BC071594
- Conserved Domains (6) summary
-
- COG0249
Location:105 → 1034
- MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
- pfam01624
Location:105 → 223
- MutS_I; MutS domain I
- pfam05188
Location:236 → 390
- MutS_II; MutS domain II
- pfam05190
Location:630 → 722
- MutS_IV; MutS family domain IV
- pfam05192
Location:437 → 525
- MutS_III; MutS domain III
- cl21455
Location:789 → 1011
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001281494.2 → NP_001268423.1 DNA mismatch repair protein Msh6 isoform 3
See identical proteins and their annotated locations for NP_001268423.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a dowstream start codon compared to variant 1. The encoded isoform (3) is shorter and has a distinct N-terminus compared to isoform 1. Variants 3 and 4 encode the same protein (isoform 3).
- Source sequence(s)
-
AC006509, AK304735, BC071594
- Conserved Domains (6) summary
-
- COG0249
Location:105 → 1034
- MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
- pfam01624
Location:105 → 223
- MutS_I; MutS domain I
- pfam05188
Location:236 → 390
- MutS_II; MutS domain II
- pfam05190
Location:630 → 722
- MutS_IV; MutS family domain IV
- pfam05192
Location:437 → 525
- MutS_III; MutS domain III
- cl21455
Location:789 → 1011
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001406795.1 → NP_001393724.1 DNA mismatch repair protein Msh6 isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406796.1 → NP_001393725.1 DNA mismatch repair protein Msh6 isoform 1
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/Swiss-Prot
- B4DF41, B4E3I4, F5H2F9, O43706, O43917, P52701, Q8TCX4, Q9BTB5
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406797.1 → NP_001393726.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
- Related
- ENSP00000501310.1, ENST00000673637.1
-
NM_001406798.1 → NP_001393727.1 DNA mismatch repair protein Msh6 isoform 10
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
- Related
- ENSP00000514752.2, ENST00000700004.2
-
NM_001406799.1 → NP_001393728.1 DNA mismatch repair protein Msh6 isoform 14
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406800.1 → NP_001393729.1 DNA mismatch repair protein Msh6 isoform 8
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406801.1 → NP_001393730.1 DNA mismatch repair protein Msh6 isoform 13
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406802.1 → NP_001393731.1 DNA mismatch repair protein Msh6 isoform 9
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406803.1 → NP_001393732.1 DNA mismatch repair protein Msh6 isoform 15
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406804.1 → NP_001393733.1 DNA mismatch repair protein Msh6 isoform 7
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406805.1 → NP_001393734.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
-
NM_001406806.1 → NP_001393735.1 DNA mismatch repair protein Msh6 isoform 14
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406807.1 → NP_001393736.1 DNA mismatch repair protein Msh6 isoform 14
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406808.1 → NP_001393737.1 DNA mismatch repair protein Msh6 isoform 6
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406809.1 → NP_001393738.1 DNA mismatch repair protein Msh6 isoform 1
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/Swiss-Prot
- B4DF41, B4E3I4, F5H2F9, O43706, O43917, P52701, Q8TCX4, Q9BTB5
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406811.1 → NP_001393740.1 DNA mismatch repair protein Msh6 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406812.1 → NP_001393741.1 DNA mismatch repair protein Msh6 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406813.1 → NP_001393742.1 DNA mismatch repair protein Msh6 isoform 5
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406814.1 → NP_001393743.1 DNA mismatch repair protein Msh6 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406815.1 → NP_001393744.1 DNA mismatch repair protein Msh6 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406816.1 → NP_001393745.1 DNA mismatch repair protein Msh6 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406817.1 → NP_001393746.1 DNA mismatch repair protein Msh6 isoform 19
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TPJ4
- Related
- ENSP00000514749.1, ENST00000700000.1
-
NM_001406818.1 → NP_001393747.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
- Related
- ENSP00000397484.2, ENST00000455383.6
-
NM_001406819.1 → NP_001393748.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
- Related
- ENSP00000390382.2, ENST00000420813.6
-
NM_001406820.1 → NP_001393749.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
- Related
- ENSP00000406248.2, ENST00000411819.2
-
NM_001406821.1 → NP_001393750.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
-
NM_001406822.1 → NP_001393751.1 DNA mismatch repair protein Msh6 isoform 13
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406823.1 → NP_001393752.1 DNA mismatch repair protein Msh6 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406824.1 → NP_001393753.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
-
NM_001406825.1 → NP_001393754.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
-
NM_001406826.1 → NP_001393755.1 DNA mismatch repair protein Msh6 isoform 18
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
-
A0A8V8TQJ0
-
NM_001406827.1 → NP_001393756.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
-
NM_001406828.1 → NP_001393757.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
-
NM_001406829.1 → NP_001393758.1 DNA mismatch repair protein Msh6 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406830.1 → NP_001393759.1 DNA mismatch repair protein Msh6 isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC006509
- UniProtKB/TrEMBL
- A0A494C0M1, A0A8V8TQJ0, C9J7Y7, C9J8Y8, C9JH55
-
NM_001406831.1 → NP_001393760.1 DNA mismatch repair protein Msh6 isoform 16
Status: REVIEWED
- Source sequence(s)
-
AC006509
-
NM_001406832.1 → NP_001393761.1 DNA mismatch repair protein Msh6 isoform 20
Status: REVIEWED
- Source sequence(s)
-
AC006509
- Related
-
ENST00000700005.1
-
NM_001407362.1 → NP_001394291.1 DNA mismatch repair protein Msh6 isoform 17
Status: REVIEWED
- Source sequence(s)
-
AC006509