U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ZNF235 zinc finger protein 235 [ Homo sapiens (human) ]

    Gene ID: 9310, updated on 9-Dec-2024

    Summary

    Official Symbol
    ZNF235provided by HGNC
    Official Full Name
    zinc finger protein 235provided by HGNC
    Primary source
    HGNC:HGNC:12866
    See related
    Ensembl:ENSG00000159917 MIM:604749; AllianceGenome:HGNC:12866
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HZF6; ZFP93; ANF270; ZNF270
    Summary
    This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein is a member of the Kruppel family of zinc finger proteins, and contains Kruppel-associated box (KRAB) A and B domains and 15 tandemly arrayed C2H2-type zinc fingers. It is an ortholog of the mouse Zfp93 protein. This gene is located in a cluster of zinc finger genes on 19q13.2. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ZNF235 in Genome Data Viewer
    Location:
    19q13.31
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (44286348..44305025, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (47109182..47127920, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (44790501..44809178, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 227 Neighboring gene uncharacterized LOC124904726 Neighboring gene zinc finger protein 233 Neighboring gene mitochondrial ribosomal protein S15 pseudogene 2 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr19:44808961-44809514 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:44810091-44810592 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:44810593-44811092 Neighboring gene NADH:ubiquinone oxidoreductase subunit A3 pseudogene 1 Neighboring gene zinc finger protein 112 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:44860641-44861141 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:44905171-44905927 Neighboring gene zinc finger protein 285

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 235
    Names
    zfp-93
    zinc finger protein 270
    zinc finger protein 6
    zinc finger protein 93 homolog
    zinc finger protein HZF6
    zinc finger protein homologous to Zfp93 in mouse
    zinc finger protein homologous to mouse Zfp93

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001411071.1NP_001398000.1  zinc finger protein 235 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC092477, AC138470, AC138473
      Consensus CDS
      CCDS92638.1
      Related
      ENSP00000497018.1, ENST00000650576.1
    2. NM_004234.4NP_004225.3  zinc finger protein 235 isoform 1

      See identical proteins and their annotated locations for NP_004225.3

      Status: REVIEWED

      Source sequence(s)
      AC092477, AC138470, AC138473
      Consensus CDS
      CCDS33048.1
      UniProtKB/Swiss-Prot
      B4DTQ7, O14898, O14899, Q14590, Q17RR8
      Related
      ENSP00000291182.3, ENST00000291182.9
      Conserved Domains (5) summary
      smart00349
      Location:868
      KRAB; krueppel associated box
      COG5048
      Location:321662
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:377397
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:847
      KRAB; KRAB box
      pfam13465
      Location:613638
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      44286348..44305025 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      47109182..47127920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)