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    MARCHF6-DT MARCHF6 divergent transcript [ Homo sapiens (human) ]

    Gene ID: 101929977, updated on 2-Nov-2024

    Summary

    Official Symbol
    MARCHF6-DTprovided by HGNC
    Official Full Name
    MARCHF6 divergent transcriptprovided by HGNC
    Primary source
    HGNC:HGNC:56238
    See related
    Ensembl:ENSG00000259802 AllianceGenome:HGNC:56238
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PACMP
    Summary
    Enables poly-ADP-D-ribose binding activity. Involved in negative regulation of protein ubiquitination and positive regulation of DNA repair. Is active in nucleolus and site of DNA damage. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See MARCHF6-DT in Genome Data Viewer
    Location:
    5p15.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (10343103..10354057, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (10282368..10293239, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (10343215..10354169, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15917 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22352 Neighboring gene carboxymethylenebutenolidase homolog Neighboring gene ReSE screen-validated silencer GRCh37_chr5:10300268-10300444 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:10307292-10307792 Neighboring gene CRISPRi-validated cis-regulatory element chr5.702 Neighboring gene Sharpr-MPRA regulatory region 12783 Neighboring gene uncharacterized LOC105374651 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15918 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:10333367-10334122 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22353 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15919 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15920 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:10354472-10355043 Neighboring gene membrane associated ring-CH-type finger 6 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22354 Neighboring gene microRNA 10397 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:10420944-10422143 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15921 Neighboring gene ROPN1L antisense RNA 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Other Names

    • CTD-2256P15.2
    • PAR-amplifying and CtIP-maintaining micropeptide
    • Poly-ADP-ribosylation-amplifying and CtIP-maintaining micropeptide

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables poly-ADP-D-ribose binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in site of DNA damage IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_183260.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC012640
    2. NR_183261.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC012640
      Related
      ENST00000705517.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      10343103..10354057 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      10282368..10293239 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)