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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001252675.2 → NP_001239604.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 2 precursor
See identical proteins and their annotated locations for NP_001239604.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AK092295, AK125923, BC044588, BM150326
- UniProtKB/TrEMBL
-
Q7Z5G3
- Conserved Domains (2) summary
-
- cd05966
Location:64 → 665
- ACS; Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme)
- TIGR02188
Location:54 → 674
- Ac_CoA_lig_AcsA; acetate--CoA ligase
-
NM_001252676.2 → NP_001239605.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK125923, AK296306, AK314440, DC404033
- Consensus CDS
-
CCDS58764.1
- UniProtKB/TrEMBL
-
Q6ZV30
- Related
- ENSP00000439304.2, ENST00000537502.5
- Conserved Domains (2) summary
-
- COG0365
Location:23 → 543
- Acs; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Lipid transport and metabolism]
- cl17068
Location:23 → 546
- AFD_class_I; Adenylate forming domain, Class I superfamily
-
NM_001252677.2 → NP_001239606.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 4 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate splice site in the 3' coding region, which results in a translational frameshift, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AK125923, AK127566, BC114612, BM150326
- Consensus CDS
-
CCDS58765.1
- UniProtKB/TrEMBL
-
Q7Z5G3
- Related
- ENSP00000388793.2, ENST00000432802.6
- Conserved Domains (2) summary
-
- pfam00501
Location:115 → 555
- AMP-binding; AMP-binding enzyme
- cl17068
Location:64 → 555
- AFD_class_I; Adenylate forming domain, Class I superfamily
-
NM_032501.4 → NP_115890.2 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 1 precursor
See identical proteins and their annotated locations for NP_115890.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AK125923, AK314440, BM150326
- Consensus CDS
-
CCDS13167.1
- UniProtKB/Swiss-Prot
- B3KXL2, B4DJZ3, D3DW48, F5H6F4, F8W7Y1, Q5TF42, Q8IV99, Q8N234, Q96JI1, Q96JX6, Q9NU28, Q9NUB1
- UniProtKB/TrEMBL
-
Q7Z5G3
- Related
- ENSP00000316924.4, ENST00000323482.9
- Conserved Domains (1) summary
-
- TIGR02188
Location:54 → 676
- Ac_CoA_lig_AcsA; acetate--CoA ligase
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000020.11 Reference GRCh38.p14 Primary Assembly
- Range
-
25006237..25058139 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006723659.2 → XP_006723722.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X2
- UniProtKB/TrEMBL
-
Q658X4
- Conserved Domains (2) summary
-
- TIGR02188
Location:54 → 471
- Ac_CoA_lig_AcsA; acetate--CoA ligase
- cl17068
Location:64 → 462
- AFD_class_I; Adenylate forming domain, Class I superfamily
-
XM_047440557.1 → XP_047296513.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X3
-
XM_047440556.1 → XP_047296512.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1
Alternate T2T-CHM13v2.0
Genomic
-
NC_060944.1 Alternate T2T-CHM13v2.0
- Range
-
25070421..25122324 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054324142.1 → XP_054180117.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X2
- UniProtKB/TrEMBL
-
Q658X4
-
XM_054324143.1 → XP_054180118.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X3
-
XM_054324141.1 → XP_054180116.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1