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    ZFP82 ZFP82 zinc finger protein [ Homo sapiens (human) ]

    Gene ID: 284406, updated on 27-Nov-2024

    Summary

    Official Symbol
    ZFP82provided by HGNC
    Official Full Name
    ZFP82 zinc finger proteinprovided by HGNC
    Primary source
    HGNC:HGNC:28682
    See related
    Ensembl:ENSG00000181007 AllianceGenome:HGNC:28682
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ZNF545
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in thyroid (RPKM 1.5), brain (RPKM 1.3) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See ZFP82 in Genome Data Viewer
    Location:
    19q13.12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (36383120..36418644, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (39058035..39093577, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (36874022..36909546, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 665 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:36818663-36819164 Neighboring gene MPRA-validated peak3460 silencer Neighboring gene ZFP14 zinc finger protein Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10548 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14522 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:36912605-36913287 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:36919277-36919778 Neighboring gene acyl-CoA thioesterase 4 pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:36919779-36920278 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr19:36939953-36941152 Neighboring gene zinc finger protein 566 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:36979559-36980446 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:36980447-36981332

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1948, MGC45380

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 82 homolog
    Names
    zinc finger protein 545
    zinc finger protein 85

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001321917.2NP_001308846.1  zinc finger protein 82 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC092296, AL707725, BX491216
      Conserved Domains (3) summary
      smart00349
      Location:666
      KRAB; krueppel associated box
      COG5048
      Location:144527
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:341361
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001321918.2NP_001308847.1  zinc finger protein 82 homolog isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC092296, BX491216
      Conserved Domains (1) summary
      smart00349
      Location:665
      KRAB; krueppel associated box
    3. NM_001321919.2NP_001308848.1  zinc finger protein 82 homolog isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC092296, BX491216
      Conserved Domains (2) summary
      smart00349
      Location:665
      KRAB; krueppel associated box
      pfam01352
      Location:645
      KRAB; KRAB box
    4. NM_133466.4NP_597723.1  zinc finger protein 82 homolog isoform 1

      See identical proteins and their annotated locations for NP_597723.1

      Status: VALIDATED

      Source sequence(s)
      AC092296, AL707725, AL834267
      Consensus CDS
      CCDS12493.1
      UniProtKB/Swiss-Prot
      Q8N141, Q8NC63, Q8TF53
      UniProtKB/TrEMBL
      D3Y299
      Related
      ENSP00000431265.1, ENST00000392161.4
      Conserved Domains (3) summary
      smart00349
      Location:665
      KRAB; krueppel associated box
      COG5048
      Location:143526
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:340360
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      36383120..36418644 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      39058035..39093577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)