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    RPS17B ribosomal 40S subunit protein S17B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852058, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPS17B
    Official Full Name
    ribosomal 40S subunit protein S17B
    Primary source
    SGD:S000002855
    Locus tag
    YDR447C
    See related
    AllianceGenome:SGD:S000002855; FungiDB:YDR447C; VEuPathDB:YDR447C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RP51B; RPL51B
    Summary
    Predicted to be a structural constituent of ribosome. Involved in ribosomal small subunit assembly. Predicted to be located in cytosol and ribosome. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 4. Orthologous to human RPS17 (ribosomal protein S17). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPS17B in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_001136.10 (1354829..1355553, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene Ecm11p Neighboring gene chromatin-binding transcription regulator ADA2 Neighboring gene snoRNA-binding rRNA-processing protein UTP6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Intramolecular structure in yeast introns aids the early steps of in vitro spliceosome assembly. Charpentier B, et al. RNA, 1996 Jun. PMID 8718681, Free PMC Article
    2. Effect of RP51 gene dosage alterations on ribosome synthesis in Saccharomyces cerevisiae. Abovich N, et al. Mol Cell Biol, 1985 Dec. PMID 3915776, Free PMC Article
    3. Two genes for ribosomal protein 51 of Saccharomyces cerevisiae complement and contribute to the ribosomes. Abovich N, et al. Mol Cell Biol, 1984 Sep. PMID 6092944, Free PMC Article
    4. Splicing enhancement in the yeast rp51b intron. Libri D, et al. RNA, 2000 Mar. PMID 10744020, Free PMC Article
    5. Structure of the 80S ribosome-Xrn1 nuclease complex. Tesina P, et al. Nat Struct Mol Biol, 2019 Apr. PMID 30911188

    See all (86) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in ribosomal small subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S17B
    NP_010735.3
    • Ribosomal protein 51 (rp51) of the small (40s) subunit; homologous to mammalian ribosomal protein S17, no bacterial homolog; RPS17B has a paralog, RPS17A, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1354829..1355553 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180755.3 → NP_010735.3  TPA: ribosomal 40S subunit protein S17B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010735.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT72, P14127
      UniProtKB/TrEMBL
      A6ZZ38, C8Z605, G2WBH8, N1NY37
      Conserved Domains (1) summary
      pfam00833
      Location:1 → 115
      Ribosomal_S17e; Ribosomal S17
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P14127.1

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