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    MROH6 maestro heat like repeat family member 6 [ Homo sapiens (human) ]

    Gene ID: 642475, updated on 9-Dec-2024

    Summary

    Official Symbol
    MROH6provided by HGNC
    Official Full Name
    maestro heat like repeat family member 6provided by HGNC
    Primary source
    HGNC:HGNC:27814
    See related
    Ensembl:ENSG00000204839 AllianceGenome:HGNC:27814
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C8orf73
    Summary
    Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in bone marrow (RPKM 5.5), esophagus (RPKM 4.2) and 21 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See MROH6 in Genome Data Viewer
    Location:
    8q24.3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (143566192..143572772, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (144715587..144723834, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (144648362..144654942, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene RN7SK pseudogene 175 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:144631415-144632004 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:144632005-144632593 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144635671-144636416 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144636417-144637160 Neighboring gene uncharacterized LOC100310756 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144640331-144640972 Neighboring gene gasdermin D Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144653451-144654300 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144659908-144660815 Neighboring gene nicotinate phosphoribosyltransferase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:144660816-144661724 Neighboring gene eukaryotic translation elongation factor 1 delta Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144671257-144671758 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144671759-144672258 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:144678233-144678832

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    maestro heat-like repeat-containing protein family member 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100878.2NP_001094348.1  maestro heat-like repeat-containing protein family member 6

      See identical proteins and their annotated locations for NP_001094348.1

      Status: VALIDATED

      Source sequence(s)
      AC067930, AL040647, BC029031, BM148864, BX341537, CD579780, DB003146, DN831781
      Consensus CDS
      CCDS47928.1
      UniProtKB/Swiss-Prot
      A6NGR9, A8MWB1
      Related
      ENSP00000381857.3, ENST00000398882.8

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      143566192..143572772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047422096.1XP_047278052.1  maestro heat-like repeat-containing protein family member 6 isoform X15

    2. XM_047422095.1XP_047278051.1  maestro heat-like repeat-containing protein family member 6 isoform X14

    3. XM_047422092.1XP_047278048.1  maestro heat-like repeat-containing protein family member 6 isoform X10

    4. XM_047422093.1XP_047278049.1  maestro heat-like repeat-containing protein family member 6 isoform X12

    5. XM_011517215.2XP_011515517.1  maestro heat-like repeat-containing protein family member 6 isoform X2

      See identical proteins and their annotated locations for XP_011515517.1

      Conserved Domains (1) summary
      PHA03247
      Location:636740
      PHA03247; large tegument protein UL36; Provisional
    6. XM_047422094.1XP_047278050.1  maestro heat-like repeat-containing protein family member 6 isoform X13

    7. XM_011517223.2XP_011515525.1  maestro heat-like repeat-containing protein family member 6 isoform X11

      See identical proteins and their annotated locations for XP_011515525.1

      Conserved Domains (1) summary
      pfam02063
      Location:2105
      MARCKS; MARCKS family
    8. XM_011517222.2XP_011515524.1  maestro heat-like repeat-containing protein family member 6 isoform X8

      See identical proteins and their annotated locations for XP_011515524.1

      Conserved Domains (1) summary
      pfam02063
      Location:2105
      MARCKS; MARCKS family
    9. XM_011517217.2XP_011515519.1  maestro heat-like repeat-containing protein family member 6 isoform X4

      See identical proteins and their annotated locations for XP_011515519.1

    10. XM_011517216.3XP_011515518.1  maestro heat-like repeat-containing protein family member 6 isoform X3

      See identical proteins and their annotated locations for XP_011515518.1

      Conserved Domains (1) summary
      PHA02682
      Location:639728
      PHA02682; ORF080 virion core protein; Provisional
    11. XM_011517214.2XP_011515516.1  maestro heat-like repeat-containing protein family member 6 isoform X1

      See identical proteins and their annotated locations for XP_011515516.1

      Conserved Domains (1) summary
      PHA03247
      Location:637741
      PHA03247; large tegument protein UL36; Provisional
    12. XM_047422089.1XP_047278045.1  maestro heat-like repeat-containing protein family member 6 isoform X7

    13. XM_011517221.3XP_011515523.1  maestro heat-like repeat-containing protein family member 6 isoform X6

      See identical proteins and their annotated locations for XP_011515523.1

      Conserved Domains (1) summary
      pfam02063
      Location:2105
      MARCKS; MARCKS family
    14. XM_047422090.1XP_047278046.1  maestro heat-like repeat-containing protein family member 6 isoform X9

    15. XM_047422097.1XP_047278053.1  maestro heat-like repeat-containing protein family member 6 isoform X17

      Related
      ENSP00000436959.1, ENST00000529971.1
    16. XM_006716615.3XP_006716678.1  maestro heat-like repeat-containing protein family member 6 isoform X16

      See identical proteins and their annotated locations for XP_006716678.1

      Conserved Domains (1) summary
      pfam02063
      Location:2105
      MARCKS; MARCKS family
    17. XM_011517220.2XP_011515522.1  maestro heat-like repeat-containing protein family member 6 isoform X5

      See identical proteins and their annotated locations for XP_011515522.1

      Conserved Domains (1) summary
      pfam02063
      Location:2105
      MARCKS; MARCKS family

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NT_187571.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      56232..64478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054328769.1XP_054184744.1  maestro heat-like repeat-containing protein family member 6 isoform X15

    2. XM_054328766.1XP_054184741.1  maestro heat-like repeat-containing protein family member 6 isoform X12

    3. XM_054328756.1XP_054184731.1  maestro heat-like repeat-containing protein family member 6 isoform X2

    4. XM_054328765.1XP_054184740.1  maestro heat-like repeat-containing protein family member 6 isoform X11

    5. XM_054328762.1XP_054184737.1  maestro heat-like repeat-containing protein family member 6 isoform X8

    6. XM_054328758.1XP_054184733.1  maestro heat-like repeat-containing protein family member 6 isoform X4

    7. XM_054328757.1XP_054184732.1  maestro heat-like repeat-containing protein family member 6 isoform X3

    8. XM_054328768.1XP_054184743.1  maestro heat-like repeat-containing protein family member 6 isoform X14

    9. XM_054328764.1XP_054184739.1  maestro heat-like repeat-containing protein family member 6 isoform X10

    10. XM_054328767.1XP_054184742.1  maestro heat-like repeat-containing protein family member 6 isoform X13

    11. XM_054328761.1XP_054184736.1  maestro heat-like repeat-containing protein family member 6 isoform X7

    12. XM_054328760.1XP_054184735.1  maestro heat-like repeat-containing protein family member 6 isoform X6

    13. XM_054328763.1XP_054184738.1  maestro heat-like repeat-containing protein family member 6 isoform X9

    14. XM_054328771.1XP_054184746.1  maestro heat-like repeat-containing protein family member 6 isoform X17

    15. XM_054328770.1XP_054184745.1  maestro heat-like repeat-containing protein family member 6 isoform X16

    16. XM_054328759.1XP_054184734.1  maestro heat-like repeat-containing protein family member 6 isoform X5

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      144715587..144723834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054361000.1XP_054216975.1  maestro heat-like repeat-containing protein family member 6 isoform X15

    2. XM_054360995.1XP_054216970.1  maestro heat-like repeat-containing protein family member 6 isoform X12

    3. XM_054360982.1XP_054216957.1  maestro heat-like repeat-containing protein family member 6 isoform X2

    4. XM_054360994.1XP_054216969.1  maestro heat-like repeat-containing protein family member 6 isoform X11

    5. XM_054360990.1XP_054216965.1  maestro heat-like repeat-containing protein family member 6 isoform X8

    6. XM_054360985.1XP_054216960.1  maestro heat-like repeat-containing protein family member 6 isoform X4

    7. XM_054360983.1XP_054216958.1  maestro heat-like repeat-containing protein family member 6 isoform X18

    8. XM_054360984.1XP_054216959.1  maestro heat-like repeat-containing protein family member 6 isoform X3

    9. XM_054360999.1XP_054216974.1  maestro heat-like repeat-containing protein family member 6 isoform X14

    10. XM_054360992.1XP_054216967.1  maestro heat-like repeat-containing protein family member 6 isoform X10

    11. XM_054360998.1XP_054216973.1  maestro heat-like repeat-containing protein family member 6 isoform X13

    12. XM_054360997.1XP_054216972.1  maestro heat-like repeat-containing protein family member 6 isoform X21

    13. XM_054360989.1XP_054216964.1  maestro heat-like repeat-containing protein family member 6 isoform X7

    14. XM_054360996.1XP_054216971.1  maestro heat-like repeat-containing protein family member 6 isoform X20

    15. XM_054360993.1XP_054216968.1  maestro heat-like repeat-containing protein family member 6 isoform X19

    16. XM_054360988.1XP_054216963.1  maestro heat-like repeat-containing protein family member 6 isoform X6

    17. XM_054360991.1XP_054216966.1  maestro heat-like repeat-containing protein family member 6 isoform X9

    18. XM_054361001.1XP_054216976.1  maestro heat-like repeat-containing protein family member 6 isoform X16

    19. XM_054360986.1XP_054216961.1  maestro heat-like repeat-containing protein family member 6 isoform X5

    20. XM_054360987.1XP_054216962.1  maestro heat-like repeat-containing protein family member 6 isoform X5