The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
-
XM_047418508.1 → XP_047274464.1 nesprin-1 isoform X25
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_017010610.2 → XP_016866099.1 nesprin-1 isoform X5
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 134
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8005 → 8215
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5937 → 6723
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:180 → 278
- CH; Calponin homology (CH) domain
- pfam10541
Location:8807 → 8838
- KASH; Nuclear envelope localization domain
- cl02488
Location:7166 → 7354
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017010609.2 → XP_016866098.1 nesprin-1 isoform X1
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5944 → 6730
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8814 → 8845
- KASH; Nuclear envelope localization domain
- cl02488
Location:7173 → 7361
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047418504.1 → XP_047274460.1 nesprin-1 isoform X12
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_047418501.1 → XP_047274457.1 nesprin-1 isoform X5
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_047418503.1 → XP_047274459.1 nesprin-1 isoform X9
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_017010608.2 → XP_016866097.1 nesprin-1 isoform X1
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5944 → 6730
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8814 → 8845
- KASH; Nuclear envelope localization domain
- cl02488
Location:7173 → 7361
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047418510.1 → XP_047274466.1 nesprin-1 isoform X27
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_006715414.2 → XP_006715477.1 nesprin-1 isoform X12
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 134
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:7988 → 8198
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:2316 → 3099
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:180 → 278
- CH; Calponin homology (CH) domain
- pfam10541
Location:8790 → 8821
- KASH; Nuclear envelope localization domain
- cl02488
Location:7149 → 7337
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047418507.1 → XP_047274463.1 nesprin-1 isoform X25
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_006715409.2 → XP_006715472.1 nesprin-1 isoform X5
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 134
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8005 → 8215
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5937 → 6723
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:180 → 278
- CH; Calponin homology (CH) domain
- pfam10541
Location:8807 → 8838
- KASH; Nuclear envelope localization domain
- cl02488
Location:7166 → 7354
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715411.2 → XP_006715474.1 nesprin-1 isoform X9
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:7995 → 8205
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5927 → 6713
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8797 → 8828
- KASH; Nuclear envelope localization domain
- cl02488
Location:7156 → 7344
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011535643.2 → XP_011533945.1 nesprin-1 isoform X24
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:7957 → 8167
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5889 → 6675
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8759 → 8790
- KASH; Nuclear envelope localization domain
- cl02488
Location:7118 → 7306
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715422.2 → XP_006715485.1 nesprin-1 isoform X23
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:7959 → 8169
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5891 → 6677
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8761 → 8792
- KASH; Nuclear envelope localization domain
- cl02488
Location:7120 → 7308
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715421.3 → XP_006715484.1 nesprin-1 isoform X22
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:7960 → 8170
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5892 → 6678
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8762 → 8793
- KASH; Nuclear envelope localization domain
- cl02488
Location:7121 → 7309
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017010615.2 → XP_016866104.1 nesprin-1 isoform X30
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_017010614.2 → XP_016866103.1 nesprin-1 isoform X21
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_047418511.1 → XP_047274467.1 nesprin-1 isoform X28
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_047418509.1 → XP_047274465.1 nesprin-1 isoform X26
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_006715420.3 → XP_006715483.1 nesprin-1 isoform X20
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:7961 → 8171
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:2340 → 3123
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8763 → 8794
- KASH; Nuclear envelope localization domain
- cl02488
Location:7122 → 7310
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047418512.1 → XP_047274468.1 nesprin-1 isoform X36
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_047418506.1 → XP_047274462.1 nesprin-1 isoform X19
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_006715417.3 → XP_006715480.1 nesprin-1 isoform X18
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (7) summary
-
- COG1511
Location:6382 → 6904
- YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:7965 → 8175
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:2340 → 3123
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8767 → 8798
- KASH; Nuclear envelope localization domain
- cl02488
Location:7126 → 7314
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017010618.2 → XP_016866107.1 nesprin-1 isoform X35
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_006715416.3 → XP_006715479.1 nesprin-1 isoform X17
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (7) summary
-
- COG1511
Location:6424 → 6946
- YhgE; Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown]
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8007 → 8217
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:2340 → 3123
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8772 → 8803
- KASH; Nuclear envelope localization domain
- cl02488
Location:7168 → 7356
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047418505.1 → XP_047274461.1 nesprin-1 isoform X13
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_006715412.3 → XP_006715475.1 nesprin-1 isoform X10
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- COG1196
Location:5941 → 6721
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8007 → 8217
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8795 → 8826
- KASH; Nuclear envelope localization domain
- cl02488
Location:7168 → 7356
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011535642.3 → XP_011533944.1 nesprin-1 isoform X4
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- COG1196
Location:5941 → 6721
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8007 → 8217
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8809 → 8840
- KASH; Nuclear envelope localization domain
- cl02488
Location:7168 → 7356
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715408.3 → XP_006715471.1 nesprin-1 isoform X3
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8008 → 8218
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5946 → 6726
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8810 → 8841
- KASH; Nuclear envelope localization domain
- cl02488
Location:7169 → 7357
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017010617.2 → XP_016866106.1 nesprin-1 isoform X34
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_017010613.2 → XP_016866102.1 nesprin-1 isoform X16
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_047418502.1 → XP_047274458.1 nesprin-1 isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_011535641.3 → XP_011533943.1 nesprin-1 isoform X2
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8011 → 8221
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5944 → 6729
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8813 → 8844
- KASH; Nuclear envelope localization domain
- cl02488
Location:7172 → 7360
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715425.3 → XP_006715488.1 nesprin-1 isoform X33
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (5) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:2340 → 3123
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- cl02488
Location:7469 → 7680
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715415.3 → XP_006715478.1 nesprin-1 isoform X15
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:2340 → 3123
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8777 → 8808
- KASH; Nuclear envelope localization domain
- cl02488
Location:7173 → 7361
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017010616.2 → XP_016866105.1 nesprin-1 isoform X32
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_006715413.3 → XP_006715476.1 nesprin-1 isoform X11
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5944 → 6730
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8791 → 8822
- KASH; Nuclear envelope localization domain
- cl02488
Location:7173 → 7361
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715424.3 → XP_006715487.1 nesprin-1 isoform X31
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (5) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:2340 → 3123
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- cl02488
Location:7469 → 7680
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715410.3 → XP_006715473.1 nesprin-1 isoform X7
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5944 → 6730
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8800 → 8831
- KASH; Nuclear envelope localization domain
- cl02488
Location:7173 → 7361
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715423.3 → XP_006715486.1 nesprin-1 isoform X29
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (5) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:2340 → 3123
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- cl02488
Location:7173 → 7361
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_006715407.2 → XP_006715470.1 nesprin-1 isoform X1
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (6) summary
-
- cd00014
Location:28 → 141
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:8012 → 8222
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:5944 → 6730
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:187 → 285
- CH; Calponin homology (CH) domain
- pfam10541
Location:8814 → 8845
- KASH; Nuclear envelope localization domain
- cl02488
Location:7173 → 7361
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017010612.2 → XP_016866101.1 nesprin-1 isoform X14
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_017010611.3 → XP_016866100.1 nesprin-1 isoform X6
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_017010619.2 → XP_016866108.1 nesprin-1 isoform X37
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (4) summary
-
- cd00176
Location:7437 → 7647
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1765 → 2548
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam10541
Location:8239 → 8270
- KASH; Nuclear envelope localization domain
- cl02488
Location:1948 → 2164
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011535644.2 → XP_011533946.1 nesprin-1 isoform X37
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (4) summary
-
- cd00176
Location:7437 → 7647
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1765 → 2548
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam10541
Location:8239 → 8270
- KASH; Nuclear envelope localization domain
- cl02488
Location:1948 → 2164
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011535645.3 → XP_011533947.1 nesprin-1 isoform X38
- UniProtKB/TrEMBL
-
A0A0C4DG40
- Conserved Domains (4) summary
-
- cd00176
Location:7268 → 7478
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1596 → 2379
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam10541
Location:8070 → 8101
- KASH; Nuclear envelope localization domain
- cl02488
Location:1779 → 1995
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047418513.1 → XP_047274469.1 nesprin-1 isoform X39
-
XM_054354908.1 → XP_054210883.1 nesprin-1 isoform X25
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354886.1 → XP_054210861.1 nesprin-1 isoform X5
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354880.1 → XP_054210855.1 nesprin-1 isoform X1
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354894.1 → XP_054210869.1 nesprin-1 isoform X12
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354884.1 → XP_054210859.1 nesprin-1 isoform X5
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354891.1 → XP_054210866.1 nesprin-1 isoform X9
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354879.1 → XP_054210854.1 nesprin-1 isoform X1
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354910.1 → XP_054210885.1 nesprin-1 isoform X27
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354907.1 → XP_054210882.1 nesprin-1 isoform X25
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354885.1 → XP_054210860.1 nesprin-1 isoform X5
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354890.1 → XP_054210865.1 nesprin-1 isoform X9
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354906.1 → XP_054210881.1 nesprin-1 isoform X24
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354905.1 → XP_054210880.1 nesprin-1 isoform X23
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354904.1 → XP_054210879.1 nesprin-1 isoform X22
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354913.1 → XP_054210888.1 nesprin-1 isoform X30
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354903.1 → XP_054210878.1 nesprin-1 isoform X21
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354911.1 → XP_054210886.1 nesprin-1 isoform X28
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354909.1 → XP_054210884.1 nesprin-1 isoform X26
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354902.1 → XP_054210877.1 nesprin-1 isoform X20
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354919.1 → XP_054210894.1 nesprin-1 isoform X36
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354901.1 → XP_054210876.1 nesprin-1 isoform X19
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354900.1 → XP_054210875.1 nesprin-1 isoform X18
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354918.1 → XP_054210893.1 nesprin-1 isoform X35
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354899.1 → XP_054210874.1 nesprin-1 isoform X17
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354895.1 → XP_054210870.1 nesprin-1 isoform X13
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354892.1 → XP_054210867.1 nesprin-1 isoform X10
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354883.1 → XP_054210858.1 nesprin-1 isoform X4
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354882.1 → XP_054210857.1 nesprin-1 isoform X3
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354917.1 → XP_054210892.1 nesprin-1 isoform X34
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354898.1 → XP_054210873.1 nesprin-1 isoform X16
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354889.1 → XP_054210864.1 nesprin-1 isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354881.1 → XP_054210856.1 nesprin-1 isoform X2
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354916.1 → XP_054210891.1 nesprin-1 isoform X33
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354897.1 → XP_054210872.1 nesprin-1 isoform X15
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354915.1 → XP_054210890.1 nesprin-1 isoform X32
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354893.1 → XP_054210868.1 nesprin-1 isoform X11
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354914.1 → XP_054210889.1 nesprin-1 isoform X31
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354888.1 → XP_054210863.1 nesprin-1 isoform X7
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354912.1 → XP_054210887.1 nesprin-1 isoform X29
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354878.1 → XP_054210853.1 nesprin-1 isoform X1
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354887.1 → XP_054210862.1 nesprin-1 isoform X6
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354896.1 → XP_054210871.1 nesprin-1 isoform X14
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354920.1 → XP_054210895.1 nesprin-1 isoform X37
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354921.1 → XP_054210896.1 nesprin-1 isoform X37
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354922.1 → XP_054210897.1 nesprin-1 isoform X38
- UniProtKB/TrEMBL
-
A0A0C4DG40
-
XM_054354923.1 → XP_054210898.1 nesprin-1 isoform X39