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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_047022.1 RefSeqGene
- Range
-
5064..290050
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_024870.4 → NP_079146.2 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform a
See identical proteins and their annotated locations for NP_079146.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
- Source sequence(s)
-
AC103783, AC104416, AJ437636, BI457806, CR936666, R05648
- Consensus CDS
-
CCDS6201.1
- UniProtKB/Swiss-Prot
- B4DFX0, Q32KL0, Q32KL1, Q6R7Q3, Q6R7Q4, Q70Z35, Q9H805, Q9H961
- UniProtKB/TrEMBL
-
A0A2X0SZ31
- Related
- ENSP00000288368.4, ENST00000288368.5
- Conserved Domains (6) summary
-
- cd00992
Location:677 → 744
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd04439
Location:382 → 462
- DEP_1_P-Rex; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 1 found in P-Rex-like proteins. The P-Rex family is the guanine-nucleotide exchange factor (GEF) for the small GTPase Rac that contains an N-terminal RhoGEF domain, two DEP and PDZ domains. Rac-GEF ...
- cd04440
Location:474 → 566
- DEP_2_P-Rex; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in P-Rex-like proteins. The P-Rex family is the guanine-nucleotide exchange factor (GEF) for the small GTPase Rac that contains an N-terminal RhoGEF domain, two DEP and PDZ domains. Rac-GEF ...
- cd01224
Location:218 → 364
- PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
- pfam00169
Location:248 → 356
- PH; PH domain
- pfam00621
Location:27 → 213
- RhoGEF; RhoGEF domain
-
NM_025170.6 → NP_079446.3 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform b
See identical proteins and their annotated locations for NP_079446.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 3' UTR and coding region compared to variant 1, that causes a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a.
- Source sequence(s)
-
AC011853, AC104416, AJ437636, AK023049, BI457806
- UniProtKB/Swiss-Prot
-
Q70Z35
- Related
-
ENST00000529398.5
- Conserved Domains (6) summary
-
- cd00992
Location:677 → 744
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd04439
Location:382 → 462
- DEP_1_P-Rex; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 1 found in P-Rex-like proteins. The P-Rex family is the guanine-nucleotide exchange factor (GEF) for the small GTPase Rac that contains an N-terminal RhoGEF domain, two DEP and PDZ domains. Rac-GEF ...
- cd04440
Location:474 → 566
- DEP_2_P-Rex; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in P-Rex-like proteins. The P-Rex family is the guanine-nucleotide exchange factor (GEF) for the small GTPase Rac that contains an N-terminal RhoGEF domain, two DEP and PDZ domains. Rac-GEF ...
- cd01224
Location:218 → 364
- PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
- pfam00169
Location:248 → 356
- PH; PH domain
- pfam00621
Location:27 → 213
- RhoGEF; RhoGEF domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000008.11 Reference GRCh38.p14 Primary Assembly
- Range
-
67952046..68237032
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047422268.1 → XP_047278224.1 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X2
-
XM_047422267.1 → XP_047278223.1 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1
- UniProtKB/TrEMBL
-
A0A2X0SZ31
Alternate T2T-CHM13v2.0
Genomic
-
NC_060932.1 Alternate T2T-CHM13v2.0
- Range
-
68378485..68663734
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054361290.1 → XP_054217265.1 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X2
-
XM_054361289.1 → XP_054217264.1 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1
- UniProtKB/TrEMBL
-
A0A2X0SZ31