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    DAL4 allantoin permease [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854846, updated on 9-Dec-2024

    Summary

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    Official Symbol
    DAL4
    Official Full Name
    allantoin permease
    Primary source
    SGD:S000001467
    Locus tag
    YIR028W
    See related
    AllianceGenome:SGD:S000001467; FungiDB:YIR028W; VEuPathDB:YIR028W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables allantoin:proton symporter activity. Involved in allantoin catabolic process and allantoin transport. Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See DAL4 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (408468..410375)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene tyrosine protein phosphatase YVH1 Neighboring gene allantoinase Neighboring gene allantoicase Neighboring gene Dcg1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Induction and inhibition of the allantoin permease in Saccharomyces cerevisiae. Sumrada R, et al. J Bacteriol, 1978 Aug. PMID 355231, Free PMC Article
    2. The allantoin and uracil permease gene sequences of Saccharomyces cerevisiae are nearly identical. Yoo HS, et al. Yeast, 1992 Dec. PMID 1293888
    3. Allantoin transport in Saccharomyces cerevisiae is regulated by two induction systems. Cooper TG, et al. J Bacteriol, 1987 Oct. PMID 2820939, Free PMC Article
    4. Regulation of allantoate transport in wild-type and mutant strains of Saccharomyces cerevisiae. Chisholm VT, et al. J Bacteriol, 1987 Apr. PMID 3549700, Free PMC Article
    5. A cluster of three genes responsible for allantoin degradation in Saccharomyces cerevisiae. Cooper TG, et al. Genetics, 1979 Jun. PMID 385448, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables allantoin:proton symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables nucleobase transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in allantoin catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in allantoin transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleobase transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in purine nucleobase metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    allantoin permease
    NP_012294.3
    • Allantoin permease; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      408468..410375
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179550.3 → NP_012294.3  TPA: allantoin permease [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012294.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVV9, Q04895
      UniProtKB/TrEMBL
      A6ZVU8, C7GLS8, C8ZAS9, G2WFV6, N1P4A5
      Conserved Domains (1) summary
      cd11482
      Location:98 → 582
      SLC-NCS1sbd_NRT1-like; nucleobase-cation-symport-1 (NCS1) transporter NRT1-like; solute-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04895.1

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