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    Insl6 insulin-like 6 [ Mus musculus (house mouse) ]

    Gene ID: 27356, updated on 9-Dec-2024

    Summary

    Official Symbol
    Insl6provided by MGI
    Official Full Name
    insulin-like 6provided by MGI
    Primary source
    MGI:MGI:1351595
    See related
    Ensembl:ENSMUSG00000050957 AllianceGenome:MGI:1351595
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RIF1
    Summary
    Predicted to enable hormone activity. Acts upstream of or within several processes, including flagellated sperm motility; male gonad development; and spermatid development. Predicted to be located in extracellular region. Is expressed in several structures, including colon; gonad; heart; hemolymphoid system gland; and liver. Orthologous to human INSL6 (insulin like 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 98.8), large intestine adult (RPKM 7.8) and 1 other tissue See more
    Orthologs
    NEW
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    Genomic context

    See Insl6 in Genome Data Viewer
    Location:
    19 C1; 19 23.82 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (29298754..29302718, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (29321354..29325318, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene 5518 Neighboring gene STARR-seq mESC enhancer starr_45881 Neighboring gene predicted gene, 41829 Neighboring gene STARR-positive B cell enhancer ABC_E11673 Neighboring gene STARR-seq mESC enhancer starr_45882 Neighboring gene Janus kinase 2 Neighboring gene STARR-seq mESC enhancer starr_45883 Neighboring gene predicted gene, 52390 Neighboring gene relaxin 1 Neighboring gene plasminogen receptor, C-terminal lysine transmembrane protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    General protein information

    Preferred Names
    insulin-like peptide INSL6
    Names
    insulin-like peptide 6
    relaxin/insulin-like factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013754.1NP_038782.1  insulin-like peptide INSL6 precursor

      See identical proteins and their annotated locations for NP_038782.1

      Status: PROVISIONAL

      Source sequence(s)
      AF143807
      Consensus CDS
      CCDS29732.1
      UniProtKB/Swiss-Prot
      Q9QY05
      UniProtKB/TrEMBL
      Q545M1
      Related
      ENSMUSP00000054488.4, ENSMUST00000052380.5
      Conserved Domains (2) summary
      cd00101
      Location:3252
      IlGF_like; Insulin/insulin-like growth factor/relaxin family; insulin family of proteins. Members include a number of active peptides which are evolutionary related including insulin, relaxin, prorelaxin, insulin-like growth factors I and II, mammalian Leydig ...
      cd04365
      Location:148185
      IlGF_relaxin_like; IlGF_like family, relaxin_like subgroup, specific to vertebrates. Members include a number of active peptides including (pro)relaxin, mammalian Leydig cell-specific insulin-like peptide (gene INSL3), early placenta insulin-like peptide (ELIP; gene INSL4), ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      29298754..29302718 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)