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    RPL5 ribosomal 60S subunit protein L5 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855972, updated on 9-Dec-2024

    Summary

    Official Symbol
    RPL5
    Official Full Name
    ribosomal 60S subunit protein L5
    Primary source
    SGD:S000006052
    Locus tag
    YPL131W
    See related
    AllianceGenome:SGD:S000006052; FungiDB:YPL131W; VEuPathDB:YPL131W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    LPI14; RPL1
    Summary
    Enables 5S rRNA binding activity. Involved in ribosomal large subunit assembly. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 6; T-cell acute lymphoblastic leukemia; and glioblastoma. Orthologous to human RPL5 (ribosomal protein L5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See RPL5 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (303121..304014)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene gluconeogenesis transcription factor RDS2 Neighboring gene Cox11p Neighboring gene Spo19p Neighboring gene TATA-binding protein-associated factor TAF14

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 5S rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables 5S rRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables 5S rRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    PubMed 
    involved_in ribosomal large subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal large subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ribosomal 60S subunit protein L5
    NP_015194.1
    • Ribosomal 60S subunit protein L5; nascent Rpl5p is bound by specific chaperone Syo1p during translation; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      303121..304014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183945.1NP_015194.1  TPA: ribosomal 60S subunit protein L5 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015194.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3N6, P26321
      UniProtKB/TrEMBL
      A6ZWC1, B3LKU4, B5VT34, C7GJ84, C8ZIP9, G2WP50, N1P1H9
      Conserved Domains (1) summary
      PTZ00069
      Location:1282
      PTZ00069; 60S ribosomal protein L5; Provisional