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    LINC00298 long intergenic non-protein coding RNA 298 [ Homo sapiens (human) ]

    Gene ID: 339788, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00298provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 298provided by HGNC
    Primary source
    HGNC:HGNC:49257
    See related
    Ensembl:ENSG00000236790 AllianceGenome:HGNC:49257
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC00298 in Genome Data Viewer
    Location:
    2p25.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (7922425..7976814, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (7946477..8000853, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (8062556..8116945, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101929861 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:8012515-8013028 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:8013543-8014056 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:8013029-8013542 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8018173-8018687 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8018688-8019201 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:8019202-8019716 Neighboring gene uncharacterized LOC105373409 Neighboring gene uncharacterized LOC101929551 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:8098775-8098955 Neighboring gene uncharacterized LOC124907727 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8160164-8160664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8160665-8161165 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8168595-8169096 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8169097-8169596 Neighboring gene long intergenic non-protein coding RNA 299 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:8226605-8227804 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15250 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8289994-8290494 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8290495-8290995 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15251 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8299141-8299642 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:8299609-8299785 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8329342-8329842 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:8333701-8334276 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15252 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8393901-8394772 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:8403947-8404533 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8417861-8418362 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8421562-8422062 Neighboring gene NANOG hESC enhancer GRCh37_chr2:8440800-8441356 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15253 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15254 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15255 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8532754-8533299 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8580531-8581030 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:8587230-8588429 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15256 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15257 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15258 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8635675-8636175 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15259 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15260 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11124 Neighboring gene CRISPRi-validated cis-regulatory element chr2.183 Neighboring gene CRISPRi-validated cis-regulatory element chr2.184 Neighboring gene CRISPRi-validated cis-regulatory element chr2.185 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15265 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15266 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8683848-8684354 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8684355-8684861 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15268 Neighboring gene Sharpr-MPRA regulatory region 11674 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8712051-8712630 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15270 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15271 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15272 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8723860-8724539 Neighboring gene long intergenic non-protein coding RNA 1814

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Developing Connections Between LINC00298 RNA and Alzheimer's Disease Through Mapping Its Interactome and Through Biochemical Characterization. Kenkpen AK, et al. J Alzheimers Dis, 2023. PMID 37574728
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Developing Connections Between LINC00298 RNA and Alzheimer's Disease Through Mapping Its Interactome and Through Biochemical Characterization.
      Title: Developing Connections Between LINC00298 RNA and Alzheimer's Disease Through Mapping Its Interactome and Through Biochemical Characterization.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Clone Names

    • AC007464.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_015405.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007463, BC105688
      Related
      ENST00000426969.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      7922425..7976814 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      7946477..8000853 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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