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    T25B9.5 Tyrosine-protein kinase [ Caenorhabditis elegans ]

    Gene ID: 188883, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T25B9.5
    Official Full Name
    Tyrosine-protein kinase
    Primary source
    WormBase:WBGene00012011
    Locus tag
    CELE_T25B9.5
    See related
    AllianceGenome:WB:WBGene00012011
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T25B9.5 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (10752359..10754785, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Cystatin domain-containing protein Neighboring gene Aminotransferase class I/classII large domain-containing protein Neighboring gene Serine/threonine-protein phosphatase Neighboring gene Tyrosine-protein kinase Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables non-membrane spanning protein tyrosine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Tyrosine-protein kinase
    NP_001293881.1
    • Confirmed by transcript evidence
    NP_501993.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10752359..10754785 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001306952.2 → NP_001293881.1  Tyrosine-protein kinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293881.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061ADQ6
      Conserved Domains (3) summary
      smart00221
      Location:180 → 436
      STYKc; Protein kinase; unclassified specificity
      smart00252
      Location:77 → 158
      SH2; Src homology 2 domains
      cd00192
      Location:184 → 437
      PTKc; Catalytic domain of Protein Tyrosine Kinases

    2. NM_069592.2 → NP_501993.1  Tyrosine-protein kinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501993.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22766
      Conserved Domains (3) summary
      smart00221
      Location:175 → 431
      STYKc; Protein kinase; unclassified specificity
      smart00252
      Location:72 → 153
      SH2; Src homology 2 domains
      cd00192
      Location:179 → 432
      PTKc; Catalytic domain of Protein Tyrosine Kinases
    Nucleotide Protein
    Heading Accession and Version

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