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    RIB5 riboflavin synthase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852559, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RIB5
    Official Full Name
    riboflavin synthase
    Primary source
    SGD:S000000460
    Locus tag
    YBR256C
    See related
    AllianceGenome:SGD:S000000460; FungiDB:YBR256C; VEuPathDB:YBR256C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables riboflavin synthase activity. Involved in riboflavin biosynthetic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RIB5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (727386..728102, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Mtc4p Neighboring gene Rcf3p Neighboring gene RNase P/RNase MRP complex subunit Neighboring gene Shg1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mapping of the rib5 gene in Saccharomyces cerevisiae using UV light as an enhancer of rad52-mediated chromosome loss. Santos MA, et al. Curr Genet, 1988 Nov. PMID 3066507
    2. Riboflavin biosynthesis in Saccharomyces cerevisiae. Cloning, characterization, and expression of the RIB5 gene encoding riboflavin synthase. Santos MA, et al. J Biol Chem, 1995 Jan 6. PMID 7814407
    3. Influence of flavin analogue structure on the catalytic activities and flavinylation reactions of recombinant human liver monoamine oxidases A and B. Miller JR, et al. J Biol Chem, 1999 Aug 13. PMID 10438531
    4. Riboflavin synthetase from yeast. Properties of complexes of the enzyme with lumazine derivatives and riboflavin. Harvey RA, et al. J Biol Chem, 1966 May 10. PMID 5946633
    5. Hexavalent chromium stimulation of riboflavin synthesis in flavinogenic yeast. Fedorovych D, et al. Biometals, 2001 Mar. PMID 11368272

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables riboflavin synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables riboflavin synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables riboflavin synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in riboflavin biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in riboflavin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in riboflavin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    riboflavin synthase
    NP_009815.1
    • Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      727386..728102 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178604.1 → NP_009815.1  TPA: riboflavin synthase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009815.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQQ3, P38145
      UniProtKB/TrEMBL
      A6ZLJ6, B3LMQ5, B5VEK5, D3UF04, N1P9M6
      Conserved Domains (1) summary
      TIGR00187
      Location:1 → 210
      ribE; riboflavin synthase, alpha subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38145.1

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