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    CG3862 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33261, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG3862provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031286
    Locus tag
    Dmel_CG3862
    See related
    AllianceGenome:FB:FBgn0031286
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3862
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity and rRNA binding activity. Predicted to be involved in mitochondrial fusion and positive regulation of mitochondrial translation. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrial inner membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Orthologous to human RCC1L (RCC1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG3862 in Genome Data Viewer
    Location:
    21E2-21E2; 2-1.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (824329..825861, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (824329..825861, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Peroxin 12 Neighboring gene Post-GPI attachment to proteins 2 Neighboring gene uncharacterized protein Neighboring gene Clipper Neighboring gene dreadlocks Neighboring gene drongo Neighboring gene long non-coding RNA:CR44060

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial fusion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrial membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG3862-PA
    RCC GEF-related protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      824329..825861 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134706.2NP_608550.1  uncharacterized protein Dmel_CG3862 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608550.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9UND2, Q9VPU0
      Related
      FBpp0077702
      Conserved Domains (2) summary
      pfam00415
      Location:402449
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:220249
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat